YIL 781 CAS: 875258-85-8
MF: C24H28FN3O2•HCl
MW: 445.96
A (GHS-R1) antagonist that improves glucose tolerance.

YIL 781 (CAS 875258-85-8)

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Alternate Names: 6-(4-Fluorophenoxy)-2-methyl-3-[[(3S)-1-(1-methylethyl)-3-piperidinyl]methyl]-4(3H)-quinazolinone
Application: YIL 781 is a (GHS-R1) antagonist that improves glucose tolerance
CAS Number: 875258-85-8
Molecular Weight: 445.96
Molecular Formula: C24H28FN3O2•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
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YIL 781 has been shown to be a ghrelin receptor antagonist that improves glucose tolerance. Under both in vivo and in vitro circumstances, YIL 781 blocks the effects of ghrelin on insulin secretion and displays no significant affinity for the motilin receptor.

Physical State :
Solid
Solubility :
Soluble in DMSO (100 mM), and ethanol (100 mM).
Storage :
Desiccate at room temperature
Ki Data :
Ghrelin receptor: Ki= 17 nM; Motilin receptor: Ki= 6 µM
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

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Certificate of Analysis

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