YB-1 Antibody (E-7): sc-398146

YB-1 Antibody (E-7) is a mouse monoclonal IgG1 antibody that detects Y-box binding protein (YB-1) in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). YB-1 monoclonal antibody (E-7) recognizes a multifunctional protein that plays a crucial role in regulating both transcription and translation, acting as a transcription factor and mRNA masking protein. YB-1 (E-7) antibody targets a protein with a modular structure featuring a highly conserved N-terminal cold-shock domain and four basic C-terminal domains rich in Arginine clusters and aromatic residues, which are essential for diverse functions. YB-1 monoclonal antibody (E-7) helps researchers study a protein involved in cell proliferation by activating growth-associated gene expression while simultaneously repressing the expression of the cell death-associated gene FAS. This dual role highlights YB-1′s importance in maintaining cellular homeostasis, as YB-1 helps control the balance between cell survival and apoptosis. YB-1 (E-7) antibody enables research into a protein that interacts with various nucleic acid structures, making anti-YB-1 antibody (E-7) an invaluable tool for studying gene regulation and cell fate decisions.

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YB-1 Antibody (E-7) References:

1. YB-1 protein: functions and regulation.  |  Lyabin, DN., et al. 2014. Wiley Interdiscip Rev RNA. 5: 95-110. PMID: 24217978
2. YB-1 is a positive regulator of KLF5 transcription factor in basal-like breast cancer.  |  Jiang, D., et al. 2022. Cell Death Differ. 29: 1283-1295. PMID: 35022570
3. Upregulated YB-1 protein promotes glioblastoma growth through a YB-1/CCT4/mLST8/mTOR pathway.  |  Wang, JZ., et al. 2022. J Clin Invest. 132: PMID: 35239512
4. YB-1 as an Oncoprotein: Functions, Regulation, Post-Translational Modifications, and Targeted Therapy.  |  Yin, Q., et al. 2022. Cells. 11: PMID: 35406781
5. Diverse Regulation of YB-1 and YB-3 Abundance in Mammals.  |  Eliseeva, IA., et al. 2022. Biochemistry (Mosc). 87: S48-S167. PMID: 35501986
6. Role of YB-1 Protein in Inflammation.  |  Rybalkina, EY. and Moiseeva, NI. 2022. Biochemistry (Mosc). 87: S94-202. PMID: 35501989
7. Upregulated PARP1 confers breast cancer resistance to CDK4/6 inhibitors via YB-1 phosphorylation.  |  Quan, C., et al. 2023. Exp Hematol Oncol. 12: 100. PMID: 38037159
8. YB-1 Is a Novel Target for the Inhibition of α-Adrenergic-Induced Hypertrophy.  |  Heger, J., et al. 2023. Int J Mol Sci. 25: PMID: 38203580
9. Exosomal YB-1 facilitates ovarian restoration by MALAT1/miR-211-5p/FOXO3 axis.  |  Zhang, M., et al. 2024. Cell Biol Toxicol. 40: 29. PMID: 38700571
10. ZO-1 interacts with YB-1 in endothelial cells to regulate stress granule formation during angiogenesis.  |  El Bakkouri, Y., et al. 2024. Nat Commun. 15: 4405. PMID: 38782923

The preferred YB-1 antibody is YB-1 Antibody (59-Q): sc-101198.