YANK2 Antibody (4A7): sc-517186

YANK2 Antibody (4A7) is a mouse monoclonal IgG2b kappa light chain antibody that detects YANK2 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-YANK2 antibody (4A7) is available as a non-conjugated format. YANK2, also known as STK32B (serine/threonine kinase 32B) or STKG6, is a crucial serine/threonine kinase consisting of 414 amino acids and characterized by its single protein kinase domain. YANK2 plays a significant role in cellular signaling by catalyzing the ATP-dependent phosphorylation of target proteins, which is vital for regulating various cellular processes such as cell division, apoptosis, and homeostasis. YANK2′s importance extends to its involvement in the phosphorylation and dephosphorylation of serine and threonine residues, a key mechanism that governs a wide array of cellular functions in eukaryotes. YANK2 interacts with several specific proteins, which may further influence its role in signaling pathways and cellular responses. Multiple isoforms of YANK2 arise from alternative splicing, adding complexity to its functional repertoire and potential regulatory mechanisms within the cell.

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YANK2 Antibody (4A7) References:

1. Mutations in a new gene in Ellis-van Creveld syndrome and Weyers acrodental dysostosis.  |  Ruiz-Perez, VL., et al. 2000. Nat Genet. 24: 283-6. PMID: 10700184
2. The protein kinase complement of the human genome.  |  Manning, G., et al. 2002. Science. 298: 1912-34. PMID: 12471243
3. Long interspersed nuclear element-1 (LINE1)-mediated deletion of EVC, EVC2, C4orf6, and STK32B in Ellis-van Creveld syndrome with borderline intelligence.  |  Temtamy, SA., et al. 2008. Hum Mutat. 29: 931-8. PMID: 18454448
4. Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling.  |  Trynka, G., et al. 2009. Gut. 58: 1078-83. PMID: 19240061
5. Protein kinase catalytic domain sequence database: identification of conserved features of primary structure and classification of family members.  |  Hanks, SK. and Quinn, AM. 1991. Methods Enzymol. 200: 38-62. PMID: 1956325
6. The protein kinase family: conserved features and deduced phylogeny of the catalytic domains.  |  Hanks, SK., et al. 1988. Science. 241: 42-52. PMID: 3291115
7. Sequence patterns in protein kinases.  |  Bairoch, A. and Claverie, JM. 1988. Nature. 331: 22. PMID: 3340146

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-YANK2 Antibody (4A7) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-YANK2 Antibody (4A7) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

YANK2 Antibody (4A7) Specifications

Alternate Product Name: YANK2

Product Clone Name: 4A7

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2b kappa light chain

Amino Acids: 314-414

Epitope Target: YANK2

Epitope Species: human

Product Reactivity/Detection: YANK2

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 100 µg IgG_2b kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for YANK2 Antibody (4A7): N/A