Date published: 2025-9-30

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Y-27632-d4

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Alternate Names:
trans-4-[(1R)-1-Aminoethyl]-N-4-pyridinyl-cyclohexanecarboxamide-d4 Dihydrochloride
Application:
Y-27632-d4 is a labeled Rock (Rho kinase) inhibitor
Molecular Weight:
342.30
Molecular Formula:
C14H21D4Cl2N3O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Y-27632-d4 is a deuterium-labeled analog of Y-27632, which is a potent and selective inhibitor of Rho-associated protein kinase (ROCK). In research, Y-27632-d4 is employed as an internal standard for mass spectrometry-based analytical methods to ensure accurate quantification of Y-27632. The presence of deuterium atoms minimally affects the biochemical properties of the compound but provides a distinguishable mass difference, which is critical for analytical purposes. Researchers use Y-27632-d4 to study the role of the ROCK signaling pathway in various cellular processes, including cell adhesion, motility, and contraction. It is also used in investigations into the potential effects of ROCK inhibition on the cytoskeleton dynamics of cells. Additionally, Y-27632-d4 aids in the elucidation of the chemical kinetics and metabolism of Y-27632, as it allows for precise tracking of the compound in biological systems without interference from endogenous compounds.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Y-27632-d4, 1 mg

sc-220394
1 mg
$286.00

Y-27632-d4, 10 mg

sc-220394A
10 mg
$2448.00