Molecular structure of Y-26763, CAS Number: 127408-31-5
Y-26763 (CAS 127408-31-5)
Alternate Names:
N-[(3S,4R)-6-Cyano-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl]-N-hydroxyacetamide
Application:
Y-26763 is a KATP (Kir6) channel opener
CAS Number:
127408-31-5
Purity:
>98%
Molecular Weight:
276.29
Molecular Formula:
C14H16N2O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Y-26763 is a KATP (Kir6) channel opener and active metabolite of Y-27152. In vitro, causes relaxation of contracted rat aortic rings (IC50 = 0.027 mM) and inhibits glucose-induced insulin secretion in isolated human pancreatic β-cells.
Y-26763 (CAS 127408-31-5) References
Nakajima et al (1992) Y-27152, a long-acting K+ channel opener with less tachycardia: antihypertensive effects in hypertensive rats and dogs in conscious state. J.Pharmacol.Exp.Ther. 261 730. Fukunari et al (1997) Y-26763 protects the canine heart from a stunning injury through opening of the KATP channels. Eur.J.Pharmacol. 323 197. Cosgrove et al (2004) Y-26763: ATP-sensitive K+ channel activation and the inhibition of insulin release from human pancreatic b-cells. Eur.J.Pharmacol. 486 133.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Y-26763, 10 mg | sc-204406 | 10 mg | $175.00 | |||
Y-26763, 50 mg | sc-204406A | 50 mg | $709.00 |