Molecular structure of Y 134, CAS Number: 849662-80-2
Y 134 (CAS 849662-80-2)
Alternate Names:
[6-Hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl]-[4-[4-(1-methylethyl)-1-piperazinyl]phenyl]methanone
Application:
Y 134 is a SERM displaying selectivity for ERα over ERβ
CAS Number:
849662-80-2
Purity:
≥98%
Molecular Weight:
472.60
Molecular Formula:
C28H28N2O3S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Available in US only.
Available in US only.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
Y 134, is a compound that has been synthesized using various methods and extensively investigated. While the exact mechanism of action for Y 134 remains incompletely understood, studies have suggested that it inhibits multiple enzymes and signaling pathways. These include the inhibition of cyclooxygenase-2 (COX-2), the inhibition of nuclear factor-kappa B (NF-κB), and the activation of the adenosine monophosphate-activated protein kinase (AMPK) pathway.
Y 134 (CAS 849662-80-2) References
- Estrogen receptor α antagonists mediate changes in CCL20 and CXCL1 secretions in the murine female reproductive tract. | Hickey, DK., et al. 2013. Am J Reprod Immunol. 69: 159-67. PMID: 23025258
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Y 134, 1 mg | sc-204405 | 1 mg | $175.00 | |||
| US: Only available in the US | ||||||