Molecular structure of Xylometazoline hydrochloride, CAS Number: 1218-35-5
Xylometazoline hydrochloride (CAS 1218-35-5)
Alternate Names:
2-(4-tert-Butyl-2,6-dimethylbenzyl)-2-imidazoline hydrochloride
Application:
Xylometazoline hydrochloride is α-adrenoceptor agonist
CAS Number:
1218-35-5
Purity:
≥98%
Molecular Weight:
280.84
Molecular Formula:
C16H24N2•HCl
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
Technical Information
Safety Information
SDS & Certificate of Analysis
α-adrenoceptor agonist; imidazoline binding site ligand.
Xylometazoline hydrochloride (CAS 1218-35-5) References
- The nasal decongestant effect of xylometazoline in the common cold. | Eccles, R., et al. 2008. Am J Rhinol. 22: 491-6. PMID: 18655753
- A comparison of xylometazoline (Otrivine) and phenylephrine/lignocaine mixture (Cophenylcaine) for the purposes of rigid nasendoscopy: a prospective, double-blind, randomised trial. | McCluney, NA., et al. 2009. J Laryngol Otol. 123: 626-30. PMID: 18847523
- Misuse of xylometazoline nasal drops by inhalation. | Anand, JS., et al. 2008. Subst Use Misuse. 43: 2163-8. PMID: 19085441
- Efficacy and safety of intranasal xylometazoline and ipratropium in patients with common cold. | Graf, P., et al. 2009. Expert Opin Pharmacother. 10: 889-908. PMID: 19351236
- Influence of intranasal sterile isotonic sea water applications on xylometazoline administration: an experimental study in pigs. | Nikolaidis, E., et al. 2010. Auris Nasus Larynx. 37: 71-6. PMID: 19414231
- Alpha-adrenoceptor agonistic activity of oxymetazoline and xylometazoline. | Haenisch, B., et al. 2010. Fundam Clin Pharmacol. 24: 729-39. PMID: 20030735
- A randomized trial of topical anesthesia comparing lidocaine versus lidocaine plus xylometazoline for unsedated transnasal upper gastrointestinal endoscopy. | Cheung, J., et al. 2010. Can J Gastroenterol. 24: 317-21. PMID: 20485707
- Xylometazoline pretreatment reduces nasotracheal intubation-related epistaxis in paediatric dental surgery. | Tong, JL. 2011. Br J Anaesth. 106: 279; author reply 279-80. PMID: 21233119
- Rosacea (erythematotelangiectatic type) effectively improved by topical xylometazoline. | Kim, JH., et al. 2011. J Dermatol. 38: 510-3. PMID: 21352348
- Reversible cardiomyopathy due to chronic use of xylometazoline topical nasal spray. | Figueiras-Graillet, LM., et al. 2013. Int J Cardiol. 164: e17-8. PMID: 23079093
- The effect of xylometazoline spray for expansion of nasal cavity. | Han, JS., et al. 2013. Korean J Anesthesiol. 65: 132-5. PMID: 24023995
- Differences between the alpha 2-adrenoceptor in rat submaxillary gland and the alpha 2A-and alpha 2B-adrenoceptor subtypes. | Michel, AD., et al. 1989. Br J Pharmacol. 98: 890-7. PMID: 2556205
- Development of an intranasal formulation containing indomethacin and xylometazoline for rhinosinusitis treatment. | Kar, M., et al. 2022. Eur Rev Med Pharmacol Sci. 26: 65-71. PMID: 36524913
Activator of:
α1D-AR, alpha1A-AR, alpha1B-AR, alpha2A-AR, alpha2B-AR, and alpha2C-AR.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Xylometazoline hydrochloride, 5 g | sc-255719 | 5 g | $164.00 |