Molecular structure of Xylazine Hydrochloride, CAS Number: 23076-35-9
Xylazine Hydrochloride (CAS 23076-35-9)
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Alternate Names:
2-(2,6-Dimethylphenylamino)-5,6-dihydro-4H-thiazine hydrochloride
Application:
Xylazine Hydrochloride is an adrenergic alpha-2 agonist
CAS Number:
23076-35-9
Purity:
≥98%
Molecular Weight:
256.79
Molecular Formula:
C12H16N2S•HCl
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Xylazine Hydrochloride is an activator of alpha2A-AR, alpha2B-AR and alpha2C-AR. It is a potent, non-narcotic, centrally acting sedative and analgesic agent derived from the alkaloid cinchonine, which is found in the bark of the Cinchona tree. Xylazine Hydrochloride may act to affect the release of neurotransmitters, including dopamine, norepinephrine, and serotonin, as well as hormones, such as cortisol and prolactin. Studies have reported anticonvulsant, anti-inflammatory, antinociceptive, and anesthetic effects of this compound.
Xylazine Hydrochloride (CAS 23076-35-9) References
- Effects of xylazine hydrochloride during isoflurane-induced anesthesia in horses. | Steffey, EP., et al. 2000. Am J Vet Res. 61: 1225-31. PMID: 11039552
- Effects of dexamethasone on emesis in cats sedated with xylazine hydrochloride. | Ho, CM., et al. 2001. Am J Vet Res. 62: 1218-21. PMID: 11497441
- Alpha adrenoceptor subtypes involved in the emetic action in dogs. | Hikasa, Y., et al. 1992. J Pharmacol Exp Ther. 261: 746-54. PMID: 1349647
- TREATMENT OF ACUTE AND CHRONIC MUSCLE SPASM WITH DIAZEPAM. | PERNIKOFF, M. 1964. Clin Med (Northfield). 71: 699-705. PMID: 15446147
- Sedative and cardiopulmonary effects of medetomidine hydrochloride and xylazine hydrochloride and their reversal with atipamezole hydrochloride in calves. | Rioja, E., et al. 2008. Am J Vet Res. 69: 319-29. PMID: 18312129
- Synergistic effect of growth hormone-releasing hormone (GHRH) and clonidine in stimulating GH release in young and old dogs. | Arce, V., et al. 1990. Brain Res. 537: 359-62. PMID: 2085787
- Pharmacokinetics and physiologic effects of intramuscularly administered xylazine hydrochloride-ketamine hydrochloride-butorphanol tartrate alone or in combination with orally administered sodium salicylate on biomarkers of pain in Holstein calves following castration and dehorning. | Baldridge, SL., et al. 2011. Am J Vet Res. 72: 1305-17. PMID: 21962272
- The use of xylazine hydrochloride in an analgesic protocol for claw treatment of lame dairy cows in lateral recumbency on a surgical tipping table. | Rizk, A., et al. 2012. Vet J. 192: 193-8. PMID: 22503720
- Effects of xylazine hydrochloride on hormonal, metabolic, and cardiorespiratory stress responses to lateral recumbency and claw trimming in dairy cows. | Rizk, A., et al. 2012. J Am Vet Med Assoc. 240: 1223-30. PMID: 22559113
- Evaluation and comparison of xylazine hydrochloride and dexmedetomidine hydrochloride for the induction of emesis in cats: 47 cases (2007-2013). | Willey, JL., et al. 2016. J Am Vet Med Assoc. 248: 923-8. PMID: 27031419
- Yohimbine hydrochloride reversal of ketamine hydrochloride and xylazine hydrochloride immobilization of Bengal tigers and effects on hematology and serum chemistries. | Seal, US., et al. 1987. J Wildl Dis. 23: 296-300. PMID: 3586208
- Immobilization of white-tailed deer with xylazine hydrochloride and ketamine hydrochloride and antagonism by tolazoline hydrochloride. | Kreeger, TJ., et al. 1986. J Wildl Dis. 22: 407-12. PMID: 3735588
- Yohimbine hydrochloride as an antagonist to xylazine hydrochloride-ketamine hydrochloride immobilization of white-tailed deer. | Mech, LD., et al. 1985. J Wildl Dis. 21: 405-10. PMID: 4078977
- Immobilization of Rocky Mountain elk with Telazol and xylazine hydrochloride, and antagonism by yohimbine hydrochloride. | Millspaugh, JJ., et al. 1995. J Wildl Dis. 31: 259-62. PMID: 8583649
Activator of:
alpha2A-AR, alpha2B-AR, and alpha2C-AR.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Xylazine Hydrochloride, 1 g | sc-220393 | 1 g | $56.00 |