XXYLT1 Antibody (G-7): sc-393607

XXYLT1 Antibody (G-7) is a mouse monoclonal IgM antibody that detects XXYLT1 in human, mouse, and rat samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). XXYLT1 (G-7) antibody is available as a non-conjugated format. XXYLT1, also known as C3orf21, is a 393 amino acid single-pass membrane protein that plays a crucial role in regulating glycosylation processes, essential for proper cell signaling and communication. XXYLT1 is located in the endoplasmic reticulum and modifies glycoproteins, impacting cell adhesion, immune response, and developmental processes. XXYLT1′s significance extends to cancer biology, as altered glycosylation patterns often correlate with tumor progression and metastasis. Encoded by a gene on human chromosome 3q29, XXYLT1 resides in a genomic region containing several genes linked to cancer and genetic disorders, making XXYLT1 relevant for both basic research and clinical applications.

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XXYLT1 Antibody (G-7) References:

1. Molecular cytogenetic dissection of human chromosomes 3 and 21 evolution.  |  Müller, S., et al. 2000. Proc Natl Acad Sci U S A. 97: 206-11. PMID: 10618396
2. [New tumor suppressor genes in hot spots of human chromosome 3: new methods of identification].  |  Braga, EA., et al. 2003. Mol Biol (Mosk). 37: 194-211. PMID: 12723467
3. Plasticity of human chromosome 3 during primate evolution.  |  Tsend-Ayush, E., et al. 2004. Genomics. 83: 193-202. PMID: 14706448
4. Genomic structure and paralogous regions of the inversion breakpoint occurring between human chromosome 3p12.3 and orangutan chromosome 2.  |  Yue, Y., et al. 2005. Cytogenet Genome Res. 108: 98-105. PMID: 15545721
5. Comparative cytogenetics of human chromosome 3q21.3 reveals a hot spot for ectopic recombination in hominoid evolution.  |  Yue, Y., et al. 2005. Genomics. 85: 36-47. PMID: 15607420
6. Evolutionarily plastic regions at human 3p21.3 coincide with tumor breakpoints identified by the 'elimination test'.  |  Darai, E., et al. 2005. Genomics. 86: 1-12. PMID: 15913951
7. The DNA sequence, annotation and analysis of human chromosome 3.  |  Muzny, DM., et al. 2006. Nature. 440: 1194-8. PMID: 16641997
8. Establishment and characterization of two uveal melanoma cell lines derived from tumors with loss of one chromosome 3.  |  Nareyeck, G., et al. 2006. Exp Eye Res. 83: 858-64. PMID: 16750193

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-XXYLT1 Antibody (G-7) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-XXYLT1 Antibody (G-7) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

XXYLT1 Antibody (G-7) Specifications

Alternate Product Name: XXYLT1

Product Clone Name: G-7

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgM kappa light chain

Amino Acids: 259-288

Epitope Target: XXYLT1

Epitope Species: human

Product Reactivity/Detection: XXYLT1 of human origin, AI480653 of mouse origin and the corresponding rat homolog

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, IHC(P), ELISA

Vialing Information: Each vial contains 200 µg IgM kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for XXYLT1 Antibody (G-7): P: Blocking Peptide