XTRP3 Antibody (C-11): sc-515119
- XTRP3 Antibody (C-11) is a mouse monoclonal IgG1 κ XTRP3 antibody provided at 200 µg/ml
- raised against amino acids 301-373 mapping within an extracellular domain of XTRP3 of human origin
- XTRP3 Antibody (C-11) is recommended for detection of XTRP3 of human origin by WB, IP, IF and ELISA
- Anti-XTRP3 Antibody (C-11) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG1 BP-HRP is the preferred secondary detection reagent for XTRP3 Antibody (C-11) for WB applications. This reagent is now offered in a bundle with XTRP3 Antibody (C-11) (see ordering information below).
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XTRP3 Antibody (C-11) is a mouse monoclonal IgG1 kappa light chain antibody that detects XTRP3 protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). XTRP3 (C-11) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. XTRP3 protein, also known as the sodium- and chloride-dependent transporter, is a member of the solute carrier (SLC6) family, which is one of the largest transporter families in the human genome, comprising 20 members. This 616-amino acid membrane protein is characterized by 12 putative transmembrane domains and several glycosylation sites, which are crucial for regulating neurotransmitter levels in the cerebrospinal fluid. Proper functioning of XTRP3 is vital for maintaining neurotransmitter homeostasis, and dysregulation has been implicated in various neurological and psychiatric disorders, making XTRP3 a potential target for transporter-based therapeutic agents. Anti-XTRP3 antibody (C-11) serves as an essential tool for researchers studying this transporter in health and disease, providing insights into expression and function across different human tissues, including the brain, kidney, lung, and small intestine.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
XTRP3 Antibody (C-11) References:
- Comparative human/murine sequence analysis of the common eliminated region 1 from human 3p21.3. | Kiss, H., et al. 2002. Mamm Genome. 13: 646-55. PMID: 12461651
- Identification of mammalian proline transporter SIT1 (SLC6A20) with characteristics of classical system imino. | Takanaga, H., et al. 2005. J Biol Chem. 280: 8974-84. PMID: 15632147
- Molecular cloning of the mouse IMINO system: an Na+- and Cl--dependent proline transporter. | Kowalczuk, S., et al. 2005. Biochem J. 386: 417-22. PMID: 15689184
- The molecular basis of neutral aminoacidurias. | Bröer, A., et al. 2006. Pflugers Arch. 451: 511-7. PMID: 16052352
- The SLC6 orphans are forming a family of amino acid transporters. | Bröer, S. 2006. Neurochem Int. 48: 559-67. PMID: 16540203
- Molecular cloning of an orphan transporter. A new member of the neurotransmitter transporter family. | Smith, KE., et al. 1995. FEBS Lett. 357: 86-92. PMID: 8001687
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
XTRP3 Antibody (C-11) | sc-515119 | 200 µg/ml | $322.00 | |||
XTRP3 Antibody (C-11): m-IgG1 BP-HRP Bundle | sc-531799 | 200 µg Ab; 20 µg BP | $361.00 | |||
XTRP3 Antibody (C-11) AC | sc-515119 AC | 500 µg/ml, 25% agarose | $424.00 | |||
XTRP3 Antibody (C-11) HRP | sc-515119 HRP | 200 µg/ml | $322.00 | |||
XTRP3 Antibody (C-11) FITC | sc-515119 FITC | 200 µg/ml | $336.00 | |||
XTRP3 Antibody (C-11) PE | sc-515119 PE | 200 µg/ml | $349.00 | |||
XTRP3 Antibody (C-11) Alexa Fluor® 488 | sc-515119 AF488 | 200 µg/ml | $364.00 | |||
XTRP3 Antibody (C-11) Alexa Fluor® 546 | sc-515119 AF546 | 200 µg/ml | $364.00 | |||
XTRP3 Antibody (C-11) Alexa Fluor® 594 | sc-515119 AF594 | 200 µg/ml | $364.00 | |||
XTRP3 Antibody (C-11) Alexa Fluor® 647 | sc-515119 AF647 | 200 µg/ml | $364.00 | |||
XTRP3 Antibody (C-11) Alexa Fluor® 680 | sc-515119 AF680 | 200 µg/ml | $364.00 | |||
XTRP3 Antibody (C-11) Alexa Fluor® 790 | sc-515119 AF790 | 200 µg/ml | $364.00 |