Date published: 2025-11-1

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XE 991 dihydrochloride (CAS 122955-42-4)

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Alternate Names:
10,10-bis(4-Pyridinylmethyl)-9(10H)-anthracenone dihydrochloride
Application:
XE 991 dihydrochloride is a potent & selective inhibitor of KCNQ voltage-gated K-channels
CAS Number:
122955-42-4
Purity:
≥99%
Molecular Weight:
449.37
Molecular Formula:
C26H20N2O•2HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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XE 991 dihydrochloride has garnered attention in neuropharmacological research due to its role as a potent blocker of Kv7 (KCNQ) potassium channels. Studies involving this compound are critical for unraveling the electrophysiological properties of these channels and their significance in neuronal excitability. Researchers utilize XE 991 dihydrochloride to dissect the contributions of Kv7 channels to various neuronal circuits, which is essential for understanding their function in the central nervous system. The compound′s specificity and efficacy in inhibiting Kv7 channels enable detailed analysis of channel behavior, offering valuable insights into the modulation of electrical signaling in neurons. Furthermore, its impact on cellular models of excitability is being examined to ascertain how Kv7 channel dysregulation may affect cellular communication, with broader implications for the understanding of nervous system conditions.


XE 991 dihydrochloride (CAS 122955-42-4) References

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Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

XE 991 dihydrochloride, 10 mg

sc-203453
10 mg
$173.00

XE 991 dihydrochloride, 50 mg

sc-203453A
50 mg
$719.00