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Xanthosine 5′-monophosphate disodium salt (CAS 25899-70-1)

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Alternate Names:
Xanthosine 5′-monophosphate disodium salt is also known as XMP.
Application:
Xanthosine 5′-monophosphate disodium salt is an intermediate in purine metabolism, important for DNA, RNA, and glycoprotein synthesis.
CAS Number:
25899-70-1
Purity:
≥98%
Molecular Weight:
408.17
Molecular Formula:
C10H11N4O9P•2Na
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Xanthosine 5′-monophosphate disodium salt is a chameleon-like nucleotide formed as an intermediate in purine metabolism. In the generation of guanosine monophosphate, Xanthosine 5′-monophosphate disodium salt is a product of the rate limiting step. It is important for DNA, RNA, and glycoprotein synthesis.


Xanthosine 5′-monophosphate disodium salt (CAS 25899-70-1) References

  1. Gene dosage effects in polyploid strains of Saccharomyces cerevisiae containing gua-1 wild-type and mutant alleles.  |  Reichert, U. and Winter, M. 1975. J Bacteriol. 124: 1041-5. PMID: 1104568
  2. Influence of mycophenolic acid on inosine 5'-monophosphate dehydrogenase activity in human peripheral blood mononuclear cells.  |  Daxecker, H., et al. 2002. Clin Chim Acta. 318: 71-7. PMID: 11880114
  3. 31P NMR studies of energy metabolism in xanthosine-5'-monophosphate overproducing Corynebacterium ammoniagenes.  |  Noguchi, Y., et al. 2003. Eur J Biochem. 270: 2622-6. PMID: 12787028
  4. Acid-base properties of xanthosine 5'-monophosphate (XMP) and of some related nucleobase derivatives in aqueous solution: micro acidity constant evaluations of the (N1)H versus the (N3)H deprotonation ambiguity.  |  Massoud, SS., et al. 2004. Chemistry. 10: 5129-37. PMID: 15372679
  5. A conditional mutant deficient in hypoxanthine-guanine phosphoribosyltransferase and xanthine phosphoribosyltransferase validates the purine salvage pathway of Leishmania donovani.  |  Boitz, JM. and Ullman, B. 2006. J Biol Chem. 281: 16084-9. PMID: 16603734
  6. Phosphonic acid-containing analogues of mycophenolic acid as inhibitors of IMPDH.  |  Watkins, WJ., et al. 2006. Bioorg Med Chem Lett. 16: 3479-83. PMID: 16621550
  7. Structure-based design, synthesis, evaluation, and crystal structures of transition state analogue inhibitors of inosine monophosphate cyclohydrolase.  |  Xu, L., et al. 2007. J Biol Chem. 282: 13033-46. PMID: 17324932
  8. Analysis of nucleosides and monophosphate nucleotides from mushrooms with reversed-phase HPLC.  |  Ranogajec, A., et al. 2010. J Sep Sci. 33: 1024-33. PMID: 20175083
  9. Modeling antibiotic and cytotoxic effects of the dimeric isoquinoline IQ-143 on metabolism and its regulation in Staphylococcus aureus, Staphylococcus epidermidis and human cells.  |  Cecil, A., et al. 2011. Genome Biol. 12: R24. PMID: 21418624
  10. MoImd4 mediates crosstalk between MoPdeH-cAMP signalling and purine metabolism to govern growth and pathogenicity in Magnaporthe oryzae.  |  Yang, L., et al. 2019. Mol Plant Pathol. 20: 500-518. PMID: 30426699
  11. Enzymatic Conversion of Cypridina Luciferyl Sulfate to Cypridina Luciferin with Coenzyme A as a Sulfate Acceptor in Cypridina (Vargula) hilgendorfii.  |  Nakamura, M., et al. 2019. Photochem Photobiol. 95: 1376-1386. PMID: 31230356
  12. Umami synergy as the scientific principle behind taste-pairing champagne and oysters.  |  Schmidt, CV., et al. 2020. Sci Rep. 10: 20077. PMID: 33208820
  13. Inosine 5'-Monophosphate Dehydrogenase Cytoophidia Neighbor Insulin Granules in Pancreatic β Cells.  |  Zhou, XL., et al. 2021. Pancreas. 50: e62-e64. PMID: 34643616
  14. Free amino acid, 5'-Nucleotide, and lipid distribution in different tissues of blue mussel (Mytilis edulis L.) determined by mass spectrometry based metabolomics.  |  Ma, LX., et al. 2022. Food Chem. 373: 131435. PMID: 34741971
  15. Effects of drying temperature on umami taste and aroma profiles of mushrooms (Suillus granulatus).  |  Hou, Z., et al. 2022. J Food Sci. 87: 1983-1998. PMID: 35340024

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Xanthosine 5′-monophosphate disodium salt, 250 mg

sc-216064
250 mg
$243.00

Xanthosine 5′-monophosphate disodium salt, 500 mg

sc-216064A
500 mg
$586.00