WST-5 (CAS 178925-55-8)
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WST-5 is a chemical that functions as a colorimetric reagent in cell proliferation and cytotoxicity assays. It is used to measure the metabolic activity of cells by undergoing a reduction reaction in the presence of cellular dehydrogenases. This reduction reaction results in the formation of a soluble formazan dye, which can be quantified spectrophotometrically. WST-5′s mechanism of action involves the conversion of the tetrazolium salt to formazan by cellular dehydrogenases in viable cells. This reaction occurs in the mitochondria of metabolically active cells, allowing for the assessment of cell viability and proliferation. WST-5 is high sensitivity and stability, making it reliable for evaluating cell viability and cytotoxicity in various experimental applications.
WST-5 (CAS 178925-55-8) References
- Inhibition of transplanted rat tumors by immunization with identical tumor cells infected with Friend virus. | Kobayashi, H., et al. 1970. J Natl Cancer Inst. 44: 11-9. PMID: 11515021
- Colorimetric cell proliferation assay for microorganisms in microtiter plate using water-soluble tetrazolium salts. | Tsukatani, T., et al. 2008. J Microbiol Methods. 75: 109-16. PMID: 18586343
- Immunofluorescence studies on the transplantable rat tumor cells infected with Friend virus. | Saito, H. 1971. Gan. 62: 253-8. PMID: 4328645
- Modification in growth of transplantable rat tumors exposed to Friend virus. | Kobayashi, H., et al. 1969. J Natl Cancer Inst. 42: 413-9. PMID: 5777490
- Flow injection spectrophotometric determination of sulfated bile acids in urine with immobilized enzyme reactors using water soluble tetrazolium blue-5 | XF Gao, YS Li, I Karube - Analytica chimica acta, 2001 - Elsevier. 15 September 2001,. Analytica Chimica Acta. Volume 443, Issue 2,: Pages 257-264.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
WST-5, 25 mg | sc-473949 | 25 mg | $190.00 | |||
WST-5, 100 mg | sc-473949A | 100 mg | $460.00 |