WSCD1 Antibody (H-5): sc-515191

WSCD1 Antibody (H-5) is a mouse monoclonal IgG1 kappa light chain antibody that detects WSCD1 of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). WSCD1 (H-5) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. WSC domain-containing protein 1 (WSCD1) is a 575 amino acid single-pass membrane protein characterized by two WSC domains, which play a crucial role in cellular responses to stress and maintaining cell wall integrity. These domains are named after yeast proteins WSC1-WSC4, which are integral to cell wall integrity and stress response pathways. A WSC domain is a putative carbohydrate-binding domain spanning approximately 90 amino acids and contains eight conserved cysteine residues, which form disulfide bridges, enhancing structural stability. WSC domains in WSCD1 suggest involvement in various signaling pathways and interactions with proteins in LDL-receptor class A and C-type lectin families, essential for cellular communication and immune responses. WSCD1 is encoded by a gene located on human chromosome 17p13.2, highlighting evolutionary conservation and potential significance in health and disease.

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WSCD1 Antibody (H-5) References:

1. Saccharomyces cerevisiae mid2p is a potential cell wall stress sensor and upstream activator of the PKC1-MPK1 cell integrity pathway.  |  Ketela, T., et al. 1999. J Bacteriol. 181: 3330-40. PMID: 10348843
2. Characterization of the Wsc1 protein, a putative receptor in the stress response of Saccharomyces cerevisiae.  |  Lodder, AL., et al. 1999. Genetics. 152: 1487-99. PMID: 10430578
3. Molecular cloning and characterization of Kremen, a novel kringle-containing transmembrane protein.  |  Nakamura, T., et al. 2001. Biochim Biophys Acta. 1518: 63-72. PMID: 11267660
4. Mutations in WSC genes for putative stress receptors result in sensitivity to multiple stress conditions and impairment of Rlm1-dependent gene expression in Saccharomyces cerevisiae.  |  Zu, T., et al. 2001. Mol Genet Genomics. 266: 142-55. PMID: 11589572
5. Mutational analysis of the cytoplasmic domain of the Wsc1 cell wall stress sensor.  |  Vay, HA., et al. 2004. Microbiology (Reading). 150: 3281-8. PMID: 15470108
6. Signaling alkaline pH stress in the yeast Saccharomyces cerevisiae through the Wsc1 cell surface sensor and the Slt2 MAPK pathway.  |  Serrano, R., et al. 2006. J Biol Chem. 281: 39785-95. PMID: 17088254
7. Novel candidate genes for ECT response prediction-a pilot study analyzing the DNA methylome of depressed patients receiving electroconvulsive therapy.  |  Moschny, N., et al. 2020. Clin Epigenetics. 12: 114. PMID: 32727556
8. GZ17-6.02 Inhibits the Growth of EGFRvIII+ Glioblastoma.  |  Choi, J., et al. 2022. Int J Mol Sci. 23: PMID: 35456993
9. Pregnancy enables antibody protection against intracellular infection.  |  Erickson, JJ., et al. 2022. Nature. 606: 769-775. PMID: 35676476
10. Genome-Wide Association Studies of Diarrhea Frequency and Duration in the First Year of Life in Bangladeshi Infants.  |  Munday, RM., et al. 2023. J Infect Dis. 228: 979-989. PMID: 36967705
11. Identification of Differentially Expressed mRNAs and miRNAs and Related Regulatory Networks in Cumulus Oophorus Complexes Associated with Fertilization.  |  Wang, C., et al. 2024. Reprod Sci. 31: 1408-1419. PMID: 38216777
12. A family of genes required for maintenance of cell wall integrity and for the stress response in Saccharomyces cerevisiae.  |  Verna, J., et al. 1997. Proc Natl Acad Sci U S A. 94: 13804-9. PMID: 9391108

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-WSCD1 Antibody (H-5) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-WSCD1 Antibody (H-5) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

WSCD1 Antibody (H-5) Specifications

Alternate Product Name: WSCD1

Product Clone Name: H-5

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids: 486-507

Epitope Target: WSCD1

Epitope Species: human

Product Reactivity/Detection: WSCD1

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for WSCD1 Antibody (H-5): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, P: Blocking Peptide, PE: Phycoerythrin