Molecular structure of WHI-P180, Hydrochloride, CAS Number: 211555-08-7
WHI-P180, Hydrochloride (CAS 211555-08-7)
Application:
WHI-P180, Hydrochloride is an IgE-mediated mast cell response inhibitor
CAS Number:
211555-08-7
Molecular Weight:
333.77
Molecular Formula:
C16H15N3O3•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
WHI-P180, Hydrochloride is a compound utilized in biological research to study Janus kinase 3 (JAK3) signaling pathways. As an inhibitor of JAK3, it provides researchers with a means to probe the effects of JAK3 inhibition on various cellular processes. The use of WHI-P180, Hydrochloride is especially relevant in the context of understanding the molecular basis of immune system disorders where JAK3 activity is implicated. It is also applied in signal transduction research to dissect the role of the JAK-STAT pathway in cell growth and differentiation. Moreover, studies involving WHI-P180, Hydrochloride contribute to the exploration of the potential for targeted modulation of JAK3 in various research models.
WHI-P180, Hydrochloride (CAS 211555-08-7) References
- Chemical interrogation of the neuronal kinome using a primary cell-based screening assay. | Al-Ali, H., et al. 2013. ACS Chem Biol. 8: 1027-36. PMID: 23480631
- Prediction of kinase inhibitor response using activity profiling, in vitro screening, and elastic net regression. | Tran, TP., et al. 2014. BMC Syst Biol. 8: 74. PMID: 24961498
Inhibitor of:
Cdk2, and Tns2.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
WHI-P180, Hydrochloride, 500 µg | sc-204396 | 500 µg | $240.00 | |||
WHI-P180, Hydrochloride, 1 mg | sc-204396A | 1 mg | $526.00 |