Molecular structure of WH-4-023, CAS Number: 837422-57-8
WH-4-023 (CAS 837422-57-8)
Alternate Names:
2,6-dimethylphenyl (2,4-dimethoxyphenyl)(2-((4-(4-methylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)carbamate KIN001-112 CID 11844351
CAS Number:
837422-57-8
Molecular Weight:
568.70
Molecular Formula:
C32H36N6O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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WH-4-023 (CAS 837422-57-8) References
- A Discovery Strategy for Selective Inhibitors of c-Src in Complex with the Focal Adhesion Kinase SH3/SH2-binding Region. | Moroco, JA., et al. 2015. Chem Biol Drug Des. 86: 144-55. PMID: 25376742
- Glucocorticoid resistance is reverted by LCK inhibition in pediatric T-cell acute lymphoblastic leukemia. | Serafin, V., et al. 2017. Blood. 130: 2750-2761. PMID: 29101238
- Targeting loss of the Hippo signaling pathway in NF2-deficient papillary kidney cancers. | Sourbier, C., et al. 2018. Oncotarget. 9: 10723-10733. PMID: 29535838
- Nuclear Entry of CRTC1 as Druggable Target of Acquired Pigmentary Disorder. | Yun, CY., et al. 2019. Theranostics. 9: 646-660. PMID: 30809299
- High ELF4 expression in human cancers is associated with worse disease outcomes and increased resistance to anticancer drugs. | Kafita, D., et al. 2021. PLoS One. 16: e0248984. PMID: 33836003
- Development and validation of a cuproptosis-related lncRNA model correlated to the cancer-associated fibroblasts enable the prediction prognosis of patients with osteosarcoma. | Wang, X., et al. 2023. J Bone Oncol. 38: 100463. PMID: 36569351
- Logic-based mechanistic machine learning on high-content images reveals how drugs differentially regulate cardiac fibroblasts. | Nelson, AR., et al. 2023. bioRxiv.. PMID: 36909540
- Generation of stable integration-free pig induced pluripotent stem cells under chemically defined culture condition. | Zhu, Q., et al. 2023. Cell Prolif. 56: e13487. PMID: 37190930
- Logic-based mechanistic machine learning on high-content images reveals how drugs differentially regulate cardiac fibroblasts. | Nelson, AR., et al. 2024. Proc Natl Acad Sci U S A. 121: e2303513121. PMID: 38266046
- Pharmacological Inhibition of Lck is Able to Revert Glucocorticoid Resistance in Pediatric T-ALL | Valentina Serafin PhD * 1, Giorgia Capuzzo * 1, Gloria Milani PhD * 1, Silvia Bresolin PhD * 1, Marica Pinazza PhD * 2, Sonia Minuzzo PhD * 3, Stefano Indraccolo MD * 2, Roberta Bortolozzi PhD * 1, Giuseppe Basso 4, Benedetta Accordi PhD * 1. 2016. Blood. 128: 838.
Inhibitor of:
3BP1, c-Fgr, c-Src, c-Yes, CESK1, CNIH2, Crk-L, Csk, Fer, Fyn, KIR2DS4, Lck BP-1, Lyn, MAIR-II, rac1, Sck, SH3PXD2B, Sin, SKAP55-R, and TK2.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
WH-4-023, 10 mg | sc-507457 | 10 mg | $172.00 |