WDR73 Antibody (4A6): sc-517123
- WDR73 Antibody (4A6) is a mouse monoclonal IgG2b κ WDR73 antibody provided at 100 µg/ml
- raised against amino acids 1-378 representing full length WDR73 of human origin
- recommended for detection of WDR73 of human origin by WB, IP and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for WDR73 Antibody (4A6). This work is in progress.
WDR73 Antibody (4A6) is a mouse monoclonal IgG2b kappa light chain antibody that detects the WDR73 protein of human origin by western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). Anti-WDR73 antibody (4A6) is available as the non-conjugated form. WDR73, consisting of 378 amino acids, is notable for its three WD repeats and is part of the WD repeat WDR73 family, which plays a crucial role in various cellular processes. These WD repeats are characterized by a conserved structure that typically forms a tertiary propeller configuration, allowing WDR73 to participate in essential regulatory mechanisms such as chromatin assembly, cell cycle control, signal transduction, RNA processing, apoptosis, and vesicular trafficking. The gene encoding WDR73 is located on human chromosome 15, a region associated with several genetic disorders, including Angelman syndrome and Prader-Willi syndrome, highlighting WDR73′s importance in maintaining cellular integrity and function. WDR73 (4A6) monoclonal antibody enables valuable insights into WDR73′s role in these critical biological processes and implications in human health.
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WDR73 Antibody (4A6) References:
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- WD-repeat proteins: structure characteristics, biological function, and their involvement in human diseases. | Li, D. and Roberts, R. 2001. Cell Mol Life Sci. 58: 2085-97. PMID: 11814058
- The WD-40 repeat. | van der Voorn, L. and Ploegh, HL. 1992. FEBS Lett. 307: 131-4. PMID: 1644165
- Diagnosis and management of patients with Marfan syndrome. | Midla, GS. 2008. JAAPA. 21: 21-5. PMID: 18323350
- Phylogenetic, structural and functional relationships between WD- and Kelch-repeat proteins. | Hudson, AM. and Cooley, L. 2008. Subcell Biochem. 48: 6-19. PMID: 18925367
- The C15orf2 gene in the Prader-Willi syndrome region is subject to genomic imprinting and positive selection. | Wawrzik, M., et al. 2010. Neurogenetics. 11: 153-61. PMID: 20020165
- Tyrosinemia type 1 and Angelman syndrome due to paternal uniparental isodisomy 15. | Ferrer-Bolufer, I., et al. 2009. J Inherit Metab Dis. 32 Suppl 1: S349-53. PMID: 20033293
- The ancient regulatory-protein family of WD-repeat proteins. | Neer, EJ., et al. 1994. Nature. 371: 297-300. PMID: 8090199
- Neuropsychiatric aspects of adult-onset Tay-Sachs disease: two case reports with several new findings. | Hurowitz, GI., et al. 1993. J Neuropsychiatry Clin Neurosci. 5: 30-6. PMID: 8428133
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
WDR73 Antibody (4A6) | sc-517123 | 100 µg/ml | $322.00 |