VZV Major Capsid Protein Antibody (3H2): sc-56999

VZV Major Capsid Protein Antibody (3H2) is a mouse monoclonal IgG1 antibody that detects VZV Major Capsid Protein of Varicella Zoster Virus origin by immunofluorescence (IF). Anti-VZV Major Capsid Protein antibody (3H2) is available as a non-conjugated format. VZV Major Capsid Protein plays a crucial role in the structure and integrity of the viral capsid, which is essential for protecting viral genome and assembling new virions. VZV Major Capsid Protein is located within the viral envelope and facilitates viral DNA encapsidation during assembly. Understanding VZV Major Capsid Protein structure is important for viral detection, diagnosis, and developing antiviral therapies and vaccines targeting VZV. VZV Major Capsid Protein serves as a key indicator of viral activity, making VZV Major Capsid Protein (3H2) antibody valuable for research and clinical applications related to Varicella Zoster Virus infections, including chickenpox and shingles.

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VZV Major Capsid Protein Antibody (3H2) References:

1. Delayed biosynthesis of varicella-zoster virus glycoprotein C: upregulation by hexamethylene bisacetamide and retinoic acid treatment of infected cells.  |  Storlie, J., et al. 2006. J Virol. 80: 9544-56. PMID: 16973558
2. Functions of Varicella-zoster virus ORF23 capsid protein in viral replication and the pathogenesis of skin infection.  |  Chaudhuri, V., et al. 2008. J Virol. 82: 10231-46. PMID: 18684828
3. Human herpesvirus 6 is closely related to human cytomegalovirus.  |  Lawrence, GL., et al. 1990. J Virol. 64: 287-99. PMID: 2152817
4. Studies on the pathogenesis of neurological diseases associated with Varicella-Zoster virus.  |  Kennedy, PG., et al. 1990. Neuropathol Appl Neurobiol. 16: 305-16. PMID: 2172854
5. DNA sequence of the major capsid protein gene of herpes simplex virus type 1.  |  Davison, AJ. and Scott, JE. 1986. J Gen Virol. 67 (Pt 10): 2279-86. PMID: 3020164
6. Near-atomic cryo-electron microscopy structures of varicella-zoster virus capsids.  |  Wang, W., et al. 2020. Nat Microbiol. 5: 1542-1552. PMID: 32895526
7. Cryo-EM structure of the varicella-zoster virus A-capsid.  |  Sun, J., et al. 2020. Nat Commun. 11: 4795. PMID: 32963252
8. Cell Culture Evolution of a Herpes Simplex Virus 1 (HSV-1)/Varicella-Zoster Virus (VZV) UL34/ORF24 Chimeric Virus Reveals Novel Functions for HSV Genes in Capsid Nuclear Egress.  |  Roller, RJ., et al. 2021. J Virol. 95: e0095721. PMID: 34523964
9. Studies on the polypeptides of varicella-zoster (V-Z) virus. II. Syntheses of viral polypeptides in infected cells.  |  Asano, Y. and Takahashi, M. 1980. Biken J. 23: 95-106. PMID: 6257229
10. Location and orientation of homologous sequences in the genomes of five herpesviruses.  |  Davison, AJ. and Wilkie, NM. 1983. J Gen Virol. 64 (Pt 9): 1927-42. PMID: 6310033
11. Purification and molecular anatomy of the varicella-zoster virion.  |  Grose, C., et al. 1983. Biken J. 26: 1-15. PMID: 6312957
12. Characterization and immunogenicity of a candidate subunit vaccine against varicella-zoster virus.  |  Davies, J., et al. 1994. Med Microbiol Immunol. 183: 105-17. PMID: 7935160

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-VZV Major Capsid Protein Antibody (3H2) has 0 citations in a variety of scientific publications.

Primary antibodies for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

VZV Major Capsid Protein Antibody (3H2) Specifications

Alternate Product Name: VZV Major Capsid Protein

Product Clone Name: 3H2

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁

Amino Acids:

Epitope Target: Major Capsid Protein

Epitope Species: VZV

Product Reactivity/Detection: the Major Capsid Protein

Species Reactivity/Detection: Varicella Zoster Virus

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: IF

Vialing Information: Each vial contains 100 µg IgG₁ in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for VZV Major Capsid Protein Antibody (3H2): N/A