VZV gH Antibody (6A6): sc-56996

VZV gH Antibody (6A6) is a mouse monoclonal IgG1 antibody that detects the VZV gH protein of Varicella Zoster Virus origin by immunofluorescence (IF). Anti-VZV gH antibody (6A6) is available as the non-conjugated format. Varicella-zoster virus (VZV) is a significant human pathogen responsible for two major diseases: childhood chickenpox (varicella) and shingles (zoster). VZV gH protein plays a crucial role in the virus′s ability to infect host cells, as VZV gH protein is essential for the fusion of the viral envelope with the host cell membrane, a process vital for viral entry and subsequent replication. VZV gH protein interacts with glycoprotein L (gL) to form a complex critical for VZV pathogenesis, facilitating viral evasion of host immune response and establishment of latency in sensory ganglia. Understanding VZV gH protein function is important for developing targeted therapies and vaccines against VZV-related diseases, as such knowledge may provide insights into mechanisms of viral entry and immune evasion.

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VZV gH Antibody (6A6) References:

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