VSTM2L Antibody (A-4): sc-376538

VSTM2L Antibody (A-4) is a mouse monoclonal IgG1 antibody that detects VSTM2L of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-VSTM2L antibody (A-4) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. VSTM2L is located in the endoplasmic reticulum and plays a crucial role in regulating cellular processes, particularly in immune responses and cell signaling. VSTM2L′s localization suggests a function in protein folding and quality control, which are essential for maintaining cellular homeostasis and preventing diseases related to protein misfolding. VSTM2L has been provisionally designated pending further characterization, and VSTM2L expression is particularly relevant in the epididymis, where VSTM2L may contribute to seminal fluid production. Additionally, chromosome 20, where VSTM2L resides, is associated with various genetic disorders, highlighting the importance of studying VSTM2L in both health and disease contexts.

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VSTM2L Antibody (A-4) References:

1. Does PRNP gene control the clinical and pathological phenotype of human spongiform transmissible encephalopathies?  |  Masullo, C. and Macchi, G. 2001. Clin Neuropathol. 20: 19-25. PMID: 11220690
2. Gerstmann-Sträussler-Scheinker syndrome,fatal familial insomnia, and kuru: a review of these less common human transmissible spongiform encephalopathies.  |  Collins, S., et al. 2001. J Clin Neurosci. 8: 387-97. PMID: 11535002
3. Early pattern of epilepsy in the ring chromosome 20 syndrome.  |  Ville, D., et al. 2006. Epilepsia. 47: 543-9. PMID: 16529619
4. Trisomy 20 mosaicism and nonmosaic trisomy 20: a report of 2 cases.  |  Joó, JG., et al. 2006. J Reprod Med. 51: 209-12. PMID: 16674019
5. Eppin: an epididymal protease inhibitor and a target for male contraception.  |  O'Rand, MG., et al. 2007. Soc Reprod Fertil Suppl. 63: 445-53. PMID: 17566290
6. A locus on chromosome 20 encompassing genes that are highly expressed in the epididymis.  |  Lundwall, A. 2007. Asian J Androl. 9: 540-4. PMID: 17589793
7. Ring chromosome 20 syndrome without deletions of the subtelomeric and CHRNA4--KCNQ2 genes loci.  |  Elghezal, H., et al. 2007. Eur J Med Genet. 50: 441-5. PMID: 17851150
8. Cellular pathways leading to neuronal dysfunction and degeneration.  |  Kazantsev, AG. 2007. Drug News Perspect. 20: 501-9. PMID: 18080037
9. The prion diseases.  |  Prusiner, SB. 1998. Brain Pathol. 8: 499-513. PMID: 9669700

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-VSTM2L Antibody (A-4) has 1 citations in a variety of scientific publications.

Primary antibodies like Anti-VSTM2L Antibody (A-4) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

VSTM2L Antibody (A-4) Specifications

Alternate Product Name: VSTM2L

Product Clone Name: A-4

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ lambda light chain

Amino Acids: 15-47

Epitope Target: VSTM2L

Epitope Species: human

Product Reactivity/Detection: VSTM2L

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgG₁ lambda light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 1 citations in various scientific publications

Available Conjugates/Forms for VSTM2L Antibody (A-4): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, P: Blocking Peptide, PE: Phycoerythrin