Date published: 2025-12-15

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VSIG8 Antibody (604CT14.1.2): sc-517376

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Datasheets
  • VSIG8 Antibody (604CT14.1.2) is a mouse monoclonal IgM VSIG8 antibody provided at 50 µl ascites
  • raised against a synthetic peptide corresponding to amino acids 331-360 in the C-terminal region of VSIG8 of human origin
  • recommended for detection of VSIG8 of mouse, rat and human origin by WB
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for VSIG8 Antibody (604CT14.1.2). This work is in progress.

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    VSIG8 Antibody (604CT14.1.2) is a mouse monoclonal IgM antibody that detects VSIG8 protein of mouse, rat, and human origin by western blotting (WB). Anti-VSIG8 antibody (604CT14.1.2) is available as the non-conjugated format. VSIG8, also known as V-set and immunoglobulin domain-containing protein 8 or C1orf204, is a 414 amino acid single-pass type I membrane protein characterized by the presence of two immunoglobulin-like V-type domains. VSIG8 plays a crucial role in immune regulation and cell signaling, particularly in T cell activation and differentiation, making VSIG8 significant for understanding immune responses and potential therapeutic targets in autoimmune diseases. VSIG8 is encoded by a gene located on human chromosome 1q23.2, which is notable for its association with various genetic disorders, including Stickler syndrome and familial adenomatous polyposis. The presence of two alternatively spliced isoforms of VSIG8 further highlights functional diversity and potential implications in different biological contexts. VSIG8 monoclonal antibody (604CT14.1.2) enables valuable insights into the mechanisms of immune modulation and VSIG8′s role in health and disease.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA

    LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences

    VSIG8 Antibody (604CT14.1.2) References:

    1. Schizophrenia and affective disorders--cosegregation with a translocation at chromosome 1q42 that directly disrupts brain-expressed genes: clinical and P300 findings in a family.  |  Blackwood, DH., et al. 2001. Am J Hum Genet. 69: 428-33. PMID: 11443544
    2. New insights into the evolution of chromosome 1.  |  Weise, A., et al. 2005. Cytogenet Genome Res. 108: 217-22. PMID: 15545733
    3. Hutchinson-Gilford progeria mutant lamin A primarily targets human vascular cells as detected by an anti-Lamin A G608G antibody.  |  McClintock, D., et al. 2006. Proc Natl Acad Sci U S A. 103: 2154-9. PMID: 16461887
    4. Cell biology: ageing nucleus gets out of shape.  |  Lans, H. and Hoeijmakers, JH. 2006. Nature. 440: 32-4. PMID: 16511477
    5. Chromosome 1 abnormalities in multiple myeloma.  |  Marzin, Y., et al. 2006. Anticancer Res. 26: 953-9. PMID: 16619492
    6. Genes and schizophrenia: beyond schizophrenia: the role of DISC1 in major mental illness.  |  Hennah, W., et al. 2006. Schizophr Bull. 32: 409-16. PMID: 16699061
    7. The DNA sequence and biological annotation of human chromosome 1.  |  Gregory, SG., et al. 2006. Nature. 441: 315-21. PMID: 16710414
    8. Genomic organization of the selectin family of leukocyte adhesion molecules on human and mouse chromosome 1.  |  Watson, ML., et al. 1990. J Exp Med. 172: 263-72. PMID: 1694218

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    VSIG8 Antibody (604CT14.1.2)

    sc-517376
    50 µl ascites
    $316.00