Molecular structure of Vitamin K2, CAS Number: 863-61-6
Vitamin K2 (CAS 863-61-6)
See product citations (2)
Alternate Names:
Menatetrenone; Menaquinone 4
CAS Number:
863-61-6
Molecular Weight:
444.65
Molecular Formula:
C31H40O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Vitamin K2, also known as menatetrenone or menaquinone (MK), is a type of vitamin K. It is one of three forms, alongside vitamin K1 (phylloquinone) and K3 (menadione). Vitamin K2 exists in various subtypes called menaquinones, which differ in the length of their isoprenoid chains. These menaquinones are denoted as MK-n, where M represents menaquinone, K represents vitamin K, and n indicates the number of isoprenoid side chain residues. Specifically, menatetrenone (MK-4) is a variant of vitamin K2 and is classified as a fat-soluble vitamin. It is predominantly found in animal-based foods such as egg yolks, liver, and cheese.
Vitamin K2 (CAS 863-61-6) References
- Effect of vitamin K2 on progression of atherosclerosis and vascular calcification in nondialyzed patients with chronic kidney disease stages 3-5. | Kurnatowska, I., et al. 2015. Pol Arch Med Wewn. 125: 631-40. PMID: 26176325
- Vitamin K2 stimulates MC3T3‑E1 osteoblast differentiation and mineralization through autophagy induction. | Li, W., et al. 2019. Mol Med Rep. 19: 3676-3684. PMID: 30896842
- Vitamin K2 Alleviates Insulin Resistance in Skeletal Muscle by Improving Mitochondrial Function Via SIRT1 Signaling. | Su, X., et al. 2021. Antioxid Redox Signal. 34: 99-117. PMID: 32253917
- Vitamin K2 promotes PI3K/AKT/HIF-1α-mediated glycolysis that leads to AMPK-dependent autophagic cell death in bladder cancer cells. | Duan, F., et al. 2020. Sci Rep. 10: 7714. PMID: 32382009
- Vitamin K2 Awareness in Sun-Protected Patients Supplementing With Vitamin D. | Abouodah, H., et al. 2021. J Drugs Dermatol. 20: 228-229. PMID: 33538554
- Molecular Mechanism of Vitamin K2 Protection against Amyloid-β-Induced Cytotoxicity. | Huang, SH., et al. 2021. Biomolecules. 11: PMID: 33805625
- Vitamin K2 Modulates Organelle Damage and Tauopathy Induced by Streptozotocin and Menadione in SH-SY5Y Cells. | Shandilya, S., et al. 2021. Antioxidants (Basel). 10: PMID: 34202933
- Retracted Note: Effects of Vitamin K2 on Osteoporosis. | Iwamoto, J., et al. 2021. Curr Pharm Des. 27: 2325. PMID: 34264184
- Vitamin K2 (Menaquinone-7) Reverses Age-Related Structural and Cognitive Deterioration in Naturally Aging Rats. | Elkattawy, HA., et al. 2022. Antioxidants (Basel). 11: PMID: 35326164
- Vitamin K2 Modulates Mitochondrial Dysfunction Induced by 6-Hydroxydopamine in SH-SY5Y Cells via Mitochondrial Quality-Control Loop. | Tang, H., et al. 2022. Nutrients. 14: PMID: 35406117
- Vitamin K2 Enhances Fat Degradation to Improve the Survival of C. elegans. | Qu, Z., et al. 2022. Front Nutr. 9: 858481. PMID: 35495953
- The Association of Vitamin K2 Level with the Glycaemic Status in Type 2 Diabetic Patients: A Case-Control Study. | Helmy, MY., et al. 2022. Indian J Endocrinol Metab. 26: 87-92. PMID: 35662764
- Efficacy and safety of vitamin K2 for postmenopausal women with osteoporosis at a long-term follow-up: meta-analysis and systematic review. | Zhou, M., et al. 2022. J Bone Miner Metab. 40: 763-772. PMID: 35711002
- Efficacy of vitamin K2 in the prevention and treatment of postmenopausal osteoporosis: A systematic review and meta-analysis of randomized controlled trials. | Ma, ML., et al. 2022. Front Public Health. 10: 979649. PMID: 36033779
- Vitamin K1 and K2 in the Diet of Patients in the Long Term after Kidney Transplantation. | Kluch, M., et al. 2022. Nutrients. 14: PMID: 36501100
Inhibitor of:
CCDC162.Activator of:
AUH, MGP, NDUFA1, NDUFS4, SDHAF1, SDHB, TERE1, TFPI-2, VKOR, VKORC1, and VKORC1L1.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Vitamin K2, 250 mg | sc-220385 | 250 mg | $143.00 | |||
Vitamin K2, 1 g | sc-220385A | 1 g | $403.00 |