Date published: 2026-4-1

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Vitamin K1 (CAS 84-80-0)

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Alternate Names:
Phylloquinone; Phytomenadione
Application:
Vitamin K1 is a chemical which occurs in green plants, algae, photosynthetic bacteria
CAS Number:
84-80-0
Purity:
≥98%
Molecular Weight:
450.69
Molecular Formula:
C31H46O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Vitamin K1 occurs widely in green plants, algae, photosynthetic bacteria. Vitamin K1, a fat-soluble vitamin, assumes a role in the production of clotting factors and various proteins essential for maintaining healthy blood coagulation. In laboratory applications, Vitamin K1 has been employed to delve into the intricate details of Vitamin K1-dependent proteins, exploring their structural and functional aspects, while also facilitating investigations into the metabolism of Vitamin K1.


Vitamin K1 (CAS 84-80-0) References

  1. Biosynthesis of vitamin K1 (phylloquinone) by plant peroxisomes and its integration into signaling molecule synthesis pathways.  |  Reumann, S. 2013. Subcell Biochem. 69: 213-29. PMID: 23821151
  2. Vitamin K1 distribution following intravenous vitamin K1-fat emulsion administration in rats.  |  Xiao, X., et al. 2015. Biomed Chromatogr. 29: 1849-58. PMID: 25967735
  3. Unexpected roles of plastoglobules (plastid lipid droplets) in vitamin K1 and E metabolism.  |  Spicher, L. and Kessler, F. 2015. Curr Opin Plant Biol. 25: 123-9. PMID: 26037391
  4. Structural Insights into Phylloquinone (Vitamin K1), Menaquinone (MK4, MK7), and Menadione (Vitamin K3) Binding to VKORC1.  |  Chatron, N., et al. 2019. Nutrients. 11: PMID: 30609653
  5. Quantitation of vitamin K1 in serum using online SPE-LC-MS/MS and the challenges of working with vitamin K.  |  Boegh Andersen, I., et al. 2019. J Chromatogr B Analyt Technol Biomed Life Sci. 1117: 41-48. PMID: 30995590
  6. Vitamin K1 prevents diabetic cataract by inhibiting lens aldose reductase 2 (ALR2) activity.  |  Thiagarajan, R., et al. 2019. Sci Rep. 9: 14684. PMID: 31604989
  7. Vitamin K1 Inhibition of Renal Crystal Formation through Matrix Gla Protein in the Kidney.  |  Li, Y., et al. 2019. Kidney Blood Press Res. 44: 1392-1403. PMID: 31639794
  8. An investigation of the pharmacological response to vitamin K1 in the rabbit.  |  Winn, MJ., et al. 1988. Br J Pharmacol. 94: 1077-84. PMID: 3207975
  9. Determination of pharmacokinetic parameters of vitamin K1 in rats after an intravenous infusion.  |  Mi, YN., et al. 2020. Clin Exp Pharmacol Physiol. 47: 1439-1447. PMID: 32222983
  10. In Search of Normality for Vitamin K1: Establishing Age-Dependent Reference Intervals in the Danish Population.  |  Boegh Andersen, I., et al. 2020. J Appl Lab Med. 5: 531-543. PMID: 32445363
  11. Identification of vitamin K1 chromenol--a novel metabolite of vitamin K1 formed in vitro by a component in blood.  |  Fasco, MJ., et al. 1987. Arch Biochem Biophys. 252: 501-6. PMID: 3813548
  12. Vitamin K1-induced localized scleroderma (morphea) with linear deposition of IgA in the basement membrane zone.  |  Alonso-Llamazares, J. and Ahmed, I. 1998. J Am Acad Dermatol. 38: 322-4. PMID: 9486707

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Vitamin K1, 1 g

sc-280189
1 g
$81.00

Vitamin K1, 5 g

sc-280189A
5 g
$166.00