Date published: 2025-10-9

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Vitamin D2 (CAS 50-14-6)

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Alternate Names:
Calciferol; Ergocalciferol; Viostero
Application:
Vitamin D2 is a cell differentiation inducer and DNA polymerase inhibitor
CAS Number:
50-14-6
Purity:
≥97%
Molecular Weight:
396.65
Molecular Formula:
C28H44O
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Vitamin D2 is the synthetic form of Vitamin D and may act to aid in the absorption of calcium and phosphorus. Vitamin D2 has a strong inhibitory effect against bladder tumor promotion by sodium saccharin and induces cell differentiation in leukemia cells. Vitamin D2 has also been shown to be an inhibitor of DNA polymerase.


Vitamin D2 (CAS 50-14-6) References

  1. Antitumor promoting effect of an active component of Polyporus, ergosterol and related compounds on rat urinary bladder carcinogenesis in a short-term test with concanavalin A.  |  Yazawa, Y., et al. 2000. Biol Pharm Bull. 23: 1298-302. PMID: 11085355
  2. 1,25-Dihydroxy vitamin D2 induces leukemia cell differentiation.  |  Yen, A., et al. 1991. In Vitro Cell Dev Biol. 27A: 518-20. PMID: 1653778
  3. The Effect of UV Irradiation on Vitamin D2 Content and Antioxidant and Antiglycation Activities of Mushrooms.  |  Gallotti, F. and Lavelli, V. 2020. Foods. 9: PMID: 32784944
  4. Efficacy of Daily Supplementation of Milk Fortified With Vitamin D2 for Three Months in Healthy School Children: A Randomized Placebo Controlled Trial.  |  Marwaha, RK., et al. 2021. Indian Pediatr. 58: 820-825. PMID: 34302325
  5. Relative Efficacy of Vitamin D2 and Vitamin D3 in Improving Vitamin D Status: Systematic Review and Meta-Analysis.  |  Balachandar, R., et al. 2021. Nutrients. 13: PMID: 34684328
  6. Effects of Dietary Supplementation with Mushroom or Vitamin D2-Enriched Mushroom Powders on Gastrointestinal Health Parameters in the Weaned Pig.  |  Dowley, A., et al. 2021. Animals (Basel). 11: PMID: 34944378
  7. Association Between Plasma Vitamin D2 and Type 2 Diabetes Mellitus.  |  Qi, JW., et al. 2022. Front Endocrinol (Lausanne). 13: 897316. PMID: 35721707
  8. Effectiveness of vitamin D2 compared with vitamin D3 replacement therapy in a primary healthcare setting: a retrospective cohort study.  |  Alayed Albarri, EM., et al. 2022. Qatar Med J. 2022: 29. PMID: 35974883
  9. Development of a two-dimensional liquid chromatography-tandem mass-spectrometry method for the determination of vitamin D2 in mushrooms.  |  Zelzer, S., et al. 2022. Anal Bioanal Chem. 414: 7565-7572. PMID: 35982251
  10. A Randomized Controlled Trial on Pleurotus eryngii Mushrooms with Antioxidant Compounds and Vitamin D2 in Managing Metabolic Disorders.  |  Kleftaki, SA., et al. 2022. Antioxidants (Basel). 11: PMID: 36358485
  11. Response to 'Cocoa and chocolate are sources of vitamin D2'.  |  Woznicki Kraft, D. and Giannotti, E. 2023. Food Chem. 417: 135862. PMID: 36933432
  12. The Retention of Vitamin D2 and 25-Hydroxyvitamin D2 in Pulse UV-Irradiated Dried Button Mushrooms (Agaricus bisporus) after 12 Months of Storage.  |  Cardwell, G., et al. 2023. Foods. 12: PMID: 37048250

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Vitamin D2, 1 g

sc-205988
1 g
$61.00

Vitamin D2, 5 g

sc-205988A
5 g
$194.00

I would like to know that is it possible to produce Vitamin D2 (Ergocalciferol) in 50,000 IU (International Units). If yes, then what will be its cost for bulk production.

Asked by: Qazi Mustafa
Thank you for your question. We currently do provide Vitamin D2 (CAS 50-14-6): sc-205988 in a 1g and 5 g quantity, and the list price is on our website. Please note that this is a research-grade chemical, and it is not intended for Diagnostic or Therapeutic use.
Answered by: Technical Support
Date published: 2020-10-09
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Rated 5 out of 5 by from BennettBennett, L. et al. (PubMed 24204618) reported that Vitamin D2-enriched button mushroom (Agaricus bisporus) improves memory in both wild type and APPswe/PS1dE9 transgenic mice. -SCBT Publication Review
Date published: 2015-06-10
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Vitamin D2 is rated 5.0 out of 5 by 1.
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