Molecular structure of Virginiamycin B, CAS Number: 3131-03-1
Virginiamycin B (CAS 3131-03-1)
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Application:
Virginiamycin B is a depsipeptide antibiotic
CAS Number:
3131-03-1
Purity:
≥95%
Molecular Weight:
866.96
Molecular Formula:
C45H54N8O10
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Virginiamycin B, classified as a macrolide antibiotic, displays inhibitory effects on the growth of bacterial species such as Clostridium, Peptostreptococcus, and Propionibacterium (with MIC90 values of 2, 0.5, and 8 μg/ml, respectively). By interacting with the 50S ribosome, Virginiamycin B effectively hinders protein synthesis. Resistance to this antibiotic arises from the presence of erythromycin ribosome methylation (erm) genes, which encode methylases that methylate the 50S ribosome, thereby impeding the binding of Virginiamycin B.
Virginiamycin B (CAS 3131-03-1) References
- Structural basis for streptogramin B resistance in Staphylococcus aureus by virginiamycin B lyase. | Korczynska, M., et al. 2007. Proc Natl Acad Sci U S A. 104: 10388-93. PMID: 17563376
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Virginiamycin B, 5 mg | sc-362038 | 5 mg | $214.00 |