Date published: 2025-10-16

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Vinylboronic acid dibutyl ester (CAS 6336-45-4)

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Application:
Vinylboronic acid dibutyl ester is a vinylation reagent
CAS Number:
6336-45-4
Purity:
97%
Molecular Weight:
184.08
Molecular Formula:
C10H21BO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Vinylboronic acid dibutyl ester (VBADE) is an organoboron compound widely employed in the synthesis of diverse organic molecules. With its versatility as a reagent, Vinylboronic acid dibutyl ester finds application in various domains, including organic synthesis, and catalysis. As a boronic acid derivative of dibutyl ester, Vinylboronic acid dibutyl ester plays a pivotal role in numerous research endeavors. Vinylboronic acid dibutyl ester, known as VBADE, holds significant prominence in scientific research, particularly within the realm of organic synthesis. The Lewis acid behavior of vinylboronic acid dibutyl ester enables it to accept electrons from other molecules, fostering chemical bonding in organic synthesis. Moreover, the boron atom present in Vinylboronic acid dibutyl ester can act as a Lewis base, allowing it to donate electrons to other molecules.


Vinylboronic acid dibutyl ester (CAS 6336-45-4) References

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  2. Design, synthesis, and anaplastic lymphoma kinase (ALK) inhibitory activity for a novel series of 2,4,8,22-tetraazatetracyclo[14.3.1.1³,⁷.1⁹,¹³]docosa-1(20),3(22),4,6,9(21),10,12,16,18-nonaene macrocycles.  |  Breslin, HJ., et al. 2012. J Med Chem. 55: 449-64. PMID: 22172029
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  4. Synthesis of trans-2-(trifluoromethyl)cyclopropanes via Suzuki reactions with an N-methyliminodiacetic acid boronate.  |  Duncton, MA. and Singh, R. 2013. Org Lett. 15: 4284-7. PMID: 23952128
  5. Total synthesis and detection of the bilirubin oxidation product (Z)-2-(3-ethenyl-4-methyl-5-oxo-1,5-dihydro-2H-pyrrol-2-ylidene)ethanamide (Z-BOX A).  |  Klopfleisch, M., et al. 2013. Org Lett. 15: 4608-11. PMID: 23980716
  6. Enantioselective synthesis of (-)-maoecrystal V by enantiodetermining C-H functionalization.  |  Lu, P., et al. 2014. J Am Chem Soc. 136: 17738-49. PMID: 25409033
  7. Investigation of Boron Distribution at the SiO2/Si Interface of Monolayer Doping.  |  Hsu, SH., et al. 2021. ACS Omega. 6: 733-738. PMID: 33458525

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Vinylboronic acid dibutyl ester, 1 g

sc-258328
1 g
$95.00