Molecular structure of Vinyl Carbamate, CAS Number: 15805-73-9
Vinyl Carbamate (CAS 15805-73-9)
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Application:
Vinyl Carbamate is a potent promutagen
CAS Number:
15805-73-9
Molecular Weight:
87.08
Molecular Formula:
C3H5NO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Vinyl Carbamate is a potent promutagen. It is mutagenic to Salmonella typhimurium TA 1535 and TA 100 in the presence of reduced nicotinamide adenine dinucleotide phosphate-fortified rat or mouse liver mitochondrial supernatant fractions. It is used as a reagent in organic synthesis and as an intermediate in the production of a variety of chemicals. It is also used as a catalyst in the production of polymers and as a stabilizer in the production of plastics.
Vinyl Carbamate (CAS 15805-73-9) References
- Chemoprevention of vinyl carbamate-induced lung tumors in strain A mice. | Gunning, WT., et al. 2000. Exp Lung Res. 26: 757-72. PMID: 11195469
- Mutation analysis of vinyl carbamate or urethane induced lung tumors in rasH2 transgenic mice. | Tomisawa, M., et al. 2003. Toxicol Lett. 142: 111-7. PMID: 12765245
- Enzymatic oxidation of ethyl carbamate to vinyl carbamate and its role as an intermediate in the formation of 1,N6-ethenoadenosine. | Guengerich, FP. and Kim, DH. 1991. Chem Res Toxicol. 4: 413-21. PMID: 1912327
- Inhibition of vinyl carbamate-induced pulmonary adenocarcinoma by indole-3-carbinol and myo-inositol in A/J mice. | Kassie, F., et al. 2010. Carcinogenesis. 31: 239-45. PMID: 19625346
- Synthesis and properties of vinyl carbamate epoxide, a possible ultimate electrophilic and carcinogenic metabolite of vinyl carbamate and ethyl carbamate. | Park, KK., et al. 1990. Biochem Biophys Res Commun. 169: 1094-8. PMID: 2194452
- Beetroot red (betanin) inhibits vinyl carbamate- and benzo(a)pyrene-induced lung tumorigenesis through apoptosis. | Zhang, Q., et al. 2013. Mol Carcinog. 52: 686-91. PMID: 22456940
- Function of the loading module in CorI and of the O-methyltransferase CorH in vinyl carbamate biosynthesis of the antibiotic corallopyronin A. | Schäberle, TF., et al. 2014. Antimicrob Agents Chemother. 58: 950-6. PMID: 24277032
- Depolymerizable Poly(O-vinyl carbamate-alt-sulfones) as Customizable Macromolecular Scaffolds for Mucosal Drug Delivery. | Kumar, K., et al. 2016. ACS Macro Lett. 5: 636-640. PMID: 28480130
- Lysosomal Reacidification Ameliorates Vinyl Carbamate-Induced Toxicity and Disruption on Lysosomal pH. | Li, Y., et al. 2020. J Agric Food Chem. 68: 8951-8961. PMID: 32806125
- Vinyl carbamate as a promutagen and a more carcinogenic analog of ethyl carbamate. | Dahl, GA., et al. 1978. Cancer Res. 38: 3793-804. PMID: 359128
- Chemoprotective properties of chlorophyllin against vinyl carbamate, p-nitrophenyl vinyl ether and their electrophilic epoxides. | Park, KK., et al. 1995. Cancer Lett. 94: 33-40. PMID: 7621442
- Vinyl carbamate epoxide, a major strong electrophilic, mutagenic and carcinogenic metabolite of vinyl carbamate and ethyl carbamate (urethane). | Park, KK., et al. 1993. Carcinogenesis. 14: 441-50. PMID: 8453720
- Inhibition of vinyl carbamate-induced hepatotoxicity, mutagenicity, and tumorigenicity by isopropyl-2-(1,3-dithietane-2-ylidene)-2-[N-(4-methylthiazol-2- yl)carbamoyl]acetate (YH439). | Kim, SG., et al. 1998. Carcinogenesis. 19: 687-90. PMID: 9600356
- Chemopreventive effects of 2-(allylthio)pyrazine on hepatic lesion, mutagenesis and tumorigenesis induced by vinyl carbamate or vinyl carbamate epoxide. | Surh, YJ., et al. 1998. Carcinogenesis. 19: 1263-7. PMID: 9683187
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Vinyl Carbamate, 1 mg | sc-213157B | 1 mg | $104.00 | |||
Vinyl Carbamate, 5 mg | sc-213157A | 5 mg | $270.00 | |||
Vinyl Carbamate, 10 mg | sc-213157 | 10 mg | $406.00 | |||
Vinyl Carbamate, 25 mg | sc-213157C | 25 mg | $1015.00 | |||
Vinyl Carbamate, 50 mg | sc-213157D | 50 mg | $2029.00 |