Molecular structure of Vincristine-d3 Sulfate, CAS Number: 2068-78-2 (unlabeled)
Vincristine-d3 Sulfate (CAS 2068-78-2 (unlabeled))
See product citations (3)
Application:
Vincristine-d3 Sulfate is a labeled vincristine-an alkaloid
CAS Number:
2068-78-2 (unlabeled)
Purity:
95%
Molecular Weight:
926.05
Molecular Formula:
C46H53D3N4O10•H2SO4
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Vincristine-d3 Sulfate is a labelled Vincristine, an antineoplastic alkaloid that can be isolated from Vinca rosea Linn. To analyze Vincristine, an HPLC-MS/MS method is employed, which involves monitoring at specific mass-to-charge ratios (m/z) of 794 and 814. The use of an acetonitrile mobile phase enables high sensitivity in the analysis. The linear range of this method extends up to 1 mg/mL, allowing for accurate quantification over a wide concentration range.
Vincristine-d3 Sulfate (CAS 2068-78-2 (unlabeled)) References
- A surface wipe sampling and LC-MS/MS method for the simultaneous detection of six antineoplastic drugs commonly handled by healthcare workers. | Jeronimo, M., et al. 2015. Anal Bioanal Chem. 407: 7083-92. PMID: 26141324
- Aerobic activated sludge transformation of vincristine and identification of the transformation products. | Kosjek, T., et al. 2018. Sci Total Environ. 610-611: 892-904. PMID: 28830049
- Wipe Sampling Method and Evaluation of Environmental Variables for Assessing Surface Contamination of 10 Antineoplastic Drugs by Liquid Chromatography/Tandem Mass Spectrometry. | Colombo, M., et al. 2017. Ann Work Expo Health. 61: 1003-1014. PMID: 29028255
- Rapid quantification of vincristine in mouse plasma using ESI-LC-MS/MS: Application to pharmacokinetic studies. | Jin, Y., et al. 2021. J Chromatogr B Analyt Technol Biomed Life Sci. 1168: 122591. PMID: 33684722
- A rapid and sensitive LC-ESI-MS/MS method for determining vincristine in micro-volumes of plasma for pediatric cancer patients. | Zhang, YY., et al. 2023. Anal Methods. 15: 1178-1187. PMID: 36799360
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Vincristine-d3 Sulfate, 1 mg | sc-220377 | 1 mg | $666.00 |