Date published: 2026-4-30

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Vildagliptin Carboxylic Acid Metabolite (CAS 565453-40-9)

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Application:
Vildagliptin Carboxylic Acid Metabolite is a major metabolite from Vildagliptin
CAS Number:
565453-40-9
Molecular Weight:
436.43
Molecular Formula:
C17H26N2O4•C2HF3O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Vildagliptin Carboxylic Acid Metabolite (VCAM) serves as a investigative tool in the study of dipeptidyl peptidase-4 (DPP-4) enzyme mechanisms, due to its pivotal role as a metabolite of vildagliptin. Vildagliptin Carboxylic Acid Metabolite is extensively used in research applications to explore the biochemical pathways and enzymatic reactions associated with the modulation of DPP-4 activity. It functions by binding to the active site of the DPP-4 enzyme, demonstrating a competitive inhibition that is valuable in elucidating the enzyme′s substrate specificity and kinetic properties. This metabolite is particularly significant in the context of diabetes research, as DPP-4 plays a key role in glucose metabolism by influencing the levels of incretin hormones, which are critical in regulating insulin secretion. Research involving Vildagliptin Carboxylic Acid Metabolite helps in understanding the metabolic pathways that influence the activity of DPP-4 and the broader implications for energy homeostasis and glucose regulation. This understanding is vital for advancing knowledge in biochemical pharmacology and the development of novel approaches to managing metabolic disorders.


Vildagliptin Carboxylic Acid Metabolite (CAS 565453-40-9) References

  1. Hydrolytic Metabolism of Cyanopyrrolidine DPP-4 Inhibitors Mediated by Dipeptidyl Peptidases.  |  Kong, F., et al. 2019. Drug Metab Dispos. 47: 238-248. PMID: 30530814
  2. Mechanistic Study on the Effect of Renal Impairment on the Pharmacokinetics of Vildagliptin and its Carboxylic Acid Metabolite.  |  Guo, Z., et al. 2022. Pharm Res. 39: 2147-2162. PMID: 35790618

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Vildagliptin Carboxylic Acid Metabolite, 5 mg

sc-213154
5 mg
$350.00