Vialinin A (CAS 858134-23-3)
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Vialinin A is primarily researched for its role in the inhibition of certain enzymes that are implicated in oxidative stress, which is a key factor in various biological processes. Studies often involve evaluating the efficacy of vialinin A in scavenging reactive oxygen species in different model systems. It is also a subject of interest in the study of signal transduction pathways, where researchers investigate how vialinin A affects the regulation of proteins that are instrumental in cellular communication processes. The mechanisms by which vialinin A interferes with the production of pro-inflammatory mediators are examined in detail to understand its possible impact on inflammation-related pathways. Furthermore, research on vialinin A encompasses the analysis of its molecular structure to determine how its interactions with other molecules may contribute to its overall activity in these biological systems.
Vialinin A (CAS 858134-23-3) References
- Vialinin A, a novel 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenger from an edible mushroom in China. | Xie, C., et al. 2005. Biosci Biotechnol Biochem. 69: 2326-32. PMID: 16377890
- First total synthesis of vialinin A, a novel and extremely potent inhibitor of TNF-alpha production. | Ye, YQ., et al. 2007. Org Lett. 9: 4131-4. PMID: 17850091
- Vialinin A, a novel potent inhibitor of TNF-alpha production from RBL-2H3 cells. | Onose, J., et al. 2008. Biol Pharm Bull. 31: 831-3. PMID: 18451502
- Anticancer activities of thelephantin O and vialinin A isolated from Thelephora aurantiotincta. | Norikura, T., et al. 2011. J Agric Food Chem. 59: 6974-9. PMID: 21630659
- Design and synthesis of a vialinin A analog with a potent inhibitory activity of TNF-α production and its transformation into a couple of bioprobes. | Ye, YQ., et al. 2012. Bioorg Med Chem Lett. 22: 2385-7. PMID: 22410084
- Total synthesis of thelephantin O, vialinin A/terrestrin A, and terrestrins B-D. | Fujiwara, K., et al. 2012. J Org Chem. 77: 5161-6. PMID: 22571724
- Inhibitory effects of vialinin A and its analog on tumor necrosis factor-α release and production from RBL-2H3 cells. | Onose, J., et al. 2012. Cell Immunol. 279: 140-4. PMID: 23246504
- Vialinin A is a ubiquitin-specific peptidase inhibitor. | Okada, K., et al. 2013. Bioorg Med Chem Lett. 23: 4328-31. PMID: 23791076
- Ubiquitin-specific peptidase 5, a target molecule of vialinin A, is a key molecule of TNF-α production in RBL-2H3 cells. | Yoshioka, Y., et al. 2013. PLoS One. 8: e80931. PMID: 24349023
- Vialinin A and thelephantin G, potent inhibitors of tumor necrosis factor-α production, inhibit sentrin/SUMO-specific protease 1 enzymatic activity. | Yoshioka, Y., et al. 2016. Bioorg Med Chem Lett. 26: 4237-40. PMID: 27491710
- Vialinin A, an Edible Mushroom-Derived p-Terphenyl Antioxidant, Prevents VEGF-Induced Neovascularization In Vitro and In Vivo. | Sonowal, H., et al. 2018. Oxid Med Cell Longev. 2018: 1052102. PMID: 29541344
- Ubiquitously specific protease 4 inhibitor-Vialinin A attenuates inflammation and fibrosis in S100-induced hepatitis mice through Rheb/mTOR signalling. | Xu, J., et al. 2021. J Cell Mol Med. 25: 1140-1150. PMID: 33295107
- Binding of Vialinin A and p-Terphenyl Derivatives to Ubiquitin-Specific Protease 4 (USP4): A Molecular Docking Study. | Bailly, C. and Vergoten, G. 2022. Molecules. 27: PMID: 36144645
- Kawasaki disease: ubiquitin-specific protease 5 promotes endothelial inflammation via TNFα-mediated signaling. | Huang, C., et al. 2022. Pediatr Res.. PMID: 36329225
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Vialinin A, 1 mg | sc-205539 | 1 mg | $128.00 |