Date published: 2026-5-20

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Veratrine hydrochloride (CAS 17666-25-0)

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CAS Number:
17666-25-0
Molecular Weight:
628.19
Molecular Formula:
C32H49NO9•HCl
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Veratrine hydrochloride is a mixture of alkaloids, including veratridine, cevadilline, sabadine, and cevadine hydrochlorides. Veratrine hydrochloride has been employed in scientific research to investigate the impact of drugs on cancer cells and to explore the metabolic pathways of specific drugs. As an inhibitor of the enzyme tyrosine kinase, it plays a role in regulating cell growth and differentiation. Through its inhibitory action on this enzyme, Veratrine hydrochloride can effectively impede cell growth and differentiation.


Veratrine hydrochloride (CAS 17666-25-0) References

  1. Correlation between steady transcortical potential and evoked response. I. Alterations in somatic receiving area induced by veratrine, strychnine, KCI, and novocaine.  |  GOLDRING, S. and O'LEARY, JL. 1954. Electroencephalogr Clin Neurophysiol. 6: 189-200. PMID: 13161842
  2. Reduction of glutamate release and protection against ischemic brain damage by BW 1003C87.  |  Meldrum, BS., et al. 1992. Brain Res. 593: 1-6. PMID: 1458310
  3. The action of veratrine, curare and strychnine on the response of medullated nerve.  |  Fromherz, H. 1933. J Physiol. 79: 67-74. PMID: 16994443
  4. Isotonic extension and shortening of the anterior retractor of the byssus of mytilus edulis.  |  Singh, I. 1938. J Physiol. 92: 232-40. PMID: 16994970
  5. Properties of tonic contractions produced by electrical stimulation of the anterior retractor of the byssus of Mytilus edulis.  |  Singh, I. 1938. J Physiol. 94: 1-12. PMID: 16995022
  6. The evaluation of whole-body plethysmography as a semiautomated method for analysis of emesis in the house musk shrew (Suncus murinus).  |  Tashiro, N., et al. 2007. J Am Assoc Lab Anim Sci. 46: 81-5. PMID: 17343358
  7. Calcium-dependent stimulation of acetylcholine release by substance P and vasoactive intestinal polypeptide.  |  Yau, WM., et al. 1986. Eur J Pharmacol. 120: 241-3. PMID: 2419150
  8. Characterization of acetylcholine release from enzyme-dissociated myenteric ganglia.  |  Yau, WM., et al. 1989. Am J Physiol. 256: G233-9. PMID: 2536238
  9. The voltage-gated sodium channel activator veratrine induces anxiogenic-like behaviors in rats.  |  Saitoh, A., et al. 2015. Behav Brain Res. 292: 316-22. PMID: 26099814
  10. The infralimbic and prelimbic medial prefrontal cortices have differential functions in the expression of anxiety-like behaviors in mice.  |  Suzuki, S., et al. 2016. Behav Brain Res. 304: 120-4. PMID: 26802727
  11. The delta opioid receptor agonist KNT-127 in the prelimbic medial prefrontal cortex attenuates veratrine-induced anxiety-like behaviors in mice.  |  Saitoh, A., et al. 2018. Behav Brain Res. 336: 77-84. PMID: 28864205
  12. Cardiac sympathetic afferent cell bodies are located in the peripheral nervous system of the cat.  |  Bosnjak, ZJ. and Kampine, JP. 1989. Circ Res. 64: 554-62. PMID: 2917380
  13. The different effects of exogenous and neuronally released norepinephrine on renin release in rat kidney cortical slices.  |  Sasaki, Y., et al. 1986. Eur J Pharmacol. 125: 457-60. PMID: 3525199
  14. Pharmacological studies on lamotrigine, a novel potential antiepileptic drug: II. Neurochemical studies on the mechanism of action.  |  Leach, MJ., et al. 1986. Epilepsia. 27: 490-7. PMID: 3757936
  15. Modulation of gallbladder motility by intrinsic cholinergic neurons.  |  Yau, WM. and Youther, ML. 1984. Am J Physiol. 247: G662-6. PMID: 6507623

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Veratrine hydrochloride, 25 mg

sc-253825
25 mg
$43.00