Molecular structure of Veratramine, HCl, CAS Number: 1258005-82-1
Veratramine, HCl (CAS 1258005-82-1)
Application:
Veratramine, HCl is an inactive control for cyclopamine, cyclopamine-KAAD, and jervine
CAS Number:
1258005-82-1
Molecular Weight:
446.07
Molecular Formula:
C27H39NO2•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Veratramine, HCl, V. californicum is a cell-permeable steroidal alkaloid that is structurally related to and is reported to serve as a suitable inactive control for Cyclopamine, Cyclopamine-KAAD (sc-221448), and Jervine in Shh (sonic hedgehog) signaling studies.
Veratramine, HCl (CAS 1258005-82-1) References
- Shh establishes an Nkx3.2/Sox9 autoregulatory loop that is maintained by BMP signals to induce somitic chondrogenesis. | Zeng, L., et al. 2002. Genes Dev. 16: 1990-2005. PMID: 12154128
- THE CHRONOTROPIC ACTION OF VERATRIDINE STUDIED BY DIRECT PERFUSION OF THE SINUS NODE THROUGH ITS ARTERY. | JAMES, TN. and NADEAU, RA. 1964. Henry Ford Hosp Med Bull. 12: 169-80. PMID: 14169485
- OBSERVATIONS ON THE APPLICATION OF THE ROBBINS-MONRO PROCESS TO SEQUENTIAL TOXICITY ASSAYS. | HAWKINS, DF. 1964. Br J Pharmacol Chemother. 22: 392-402. PMID: 14190474
- The teratogenic Veratrum alkaloid cyclopamine inhibits sonic hedgehog signal transduction. | Incardona, JP., et al. 1998. Development. 125: 3553-62. PMID: 9716521
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Veratramine, HCl, 5 mg | sc-356191 | 5 mg | $240.00 |