Molecular structure of VEGFR Tyrosine Kinase Inhibitor V
VEGFR Tyrosine Kinase Inhibitor V (CAS 861874-34-2 anhydrous)
Application:
VEGFR Tyrosine Kinase Inhibitor V is a potent antagonist of VEGFR activity and HUVEC proliferation
CAS Number:
861874-34-2 anhydrous
Molecular Weight:
414.45 (anhydrous free base basis)
Molecular Formula:
C25H22N2O4•xHCl•xH2O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
VEGFR Tyrosine Kinase Inhibitor V is a potent, cell-permeable antagonist of the VEGF receptor family via binding to the ATP-pocket. Studies indicate the compound reduces angiogenesis and inhibits HUVEC proliferation.
VEGFR Tyrosine Kinase Inhibitor V (CAS 861874-34-2 anhydrous) References
- Evaluation of a series of naphthamides as potent, orally active vascular endothelial growth factor receptor-2 tyrosine kinase inhibitors. | Weiss, MM., et al. 2008. J Med Chem. 51: 1668-80. PMID: 18324759
- Naphthamides as novel and potent vascular endothelial growth factor receptor tyrosine kinase inhibitors: design, synthesis, and evaluation. | Harmange, JC., et al. 2008. J Med Chem. 51: 1649-67. PMID: 18324761
- Prevention of palatable diet-induced hyperphagia in rats by central injection of a VEGFR kinase inhibitor. | Branch, A., et al. 2015. Behav Brain Res. 278: 506-13. PMID: 25448434
Inhibitor of:
c-Fms-CSF-1R, c-Kit, Flk-1, Flt, Flt-4, Lyn, Ret, and Tyrosine Kinase.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
VEGFR Tyrosine Kinase Inhibitor V, 5 mg | sc-356190 | 5 mg | $240.00 |