Date published: 2025-12-24

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Varicella Zoster Virus NP Antibody (NCP-1): sc-58072

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Datasheets
  • Varicella Zoster Virus NP Antibody (NCP-1) is a mouse monoclonal IgG1 Varicella Zoster Virus NP antibody provided at 100 µg/ml
  • raised against Varicella Zoster Virus Ellen Strain from infected monkey kidney BSC-1 cells
  • recommended for detection of the 155 kDa nucleocapsid protein of Varicella Zoster Virus Ellen strain origin by IP and IF
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Varicella Zoster Virus NP Antibody (NCP-1). This work is in progress.

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    Varicella Zoster Virus NP Antibody (NCP-1) is a mouse monoclonal IgG1 antibody that detects the Varicella Zoster Virus NP protein of Varicella Zoster Virus Ellen strain origin by immunoprecipitation (IP) and immunofluorescence (IF). Anti-Varicella Zoster Virus NP antibody (NCP-1) is available as the non-conjugated format. Varicella Zoster Virus, commonly referred to as VZV, is a significant human pathogen responsible for two major diseases: childhood chickenpox (varicella) and shingles (zoster). Understanding the structure of Varicella Zoster Virus NP protein is crucial, as VZV NP plays a vital role in viral replication and immune response evasion. Varicella Zoster Virus NP protein serves as a key component of the viral nucleocapsid, providing structural integrity and protecting the viral genome. VZV NP protein interaction with other viral proteins is essential for new virion assembly and aids in viral genome transport into the host cell nucleus. Varicella Zoster Virus NP protein′s ability to form complexes with other viral proteins enhances viral capacity to manipulate host cellular machinery, facilitating efficient viral replication. Using Varicella Zoster Virus NP (NCP-1) monoclonal antibody in research can provide valuable insights into VZV pathogenesis mechanisms and contribute to developing targeted therapies for VZV-related diseases.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA

    LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences

    Varicella Zoster Virus NP Antibody (NCP-1) References:

    1. Transcription factor Sp1 is involved in the regulation of varicella-zoster virus glycoprotein E.  |  Rahaus, M. and Wolff, MH. 2000. Virus Res. 69: 69-81. PMID: 10989187
    2. Essential role played by the C-terminal domain of glycoprotein I in envelopment of varicella-zoster virus in the trans-Golgi network: interactions of glycoproteins with tegument.  |  Wang, ZH., et al. 2001. J Virol. 75: 323-40. PMID: 11119602
    3. Varicella-Zoster virus infections of the nervous system: clinical and pathologic correlates.  |  Kleinschmidt-DeMasters, BK. and Gilden, DH. 2001. Arch Pathol Lab Med. 125: 770-80. PMID: 11371229
    4. Varicella-zoster virus glycoproteins E and I expressed in insect cells form a heterodimer that requires the N-terminal domain of glycoprotein I.  |  Kimura, H., et al. 1997. Virology. 233: 382-91. PMID: 9217061
    5. Varicella-zoster virus glycoprotein I is essential for growth of virus in Vero cells.  |  Cohen, JI. and Nguyen, H. 1997. J Virol. 71: 6913-20. PMID: 9261418
    6. Mutational analysis of the role of glycoprotein I in varicella-zoster virus replication and its effects on glycoprotein E conformation and trafficking.  |  Mallory, S., et al. 1997. J Virol. 71: 8279-88. PMID: 9343180

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    Varicella Zoster Virus NP Antibody (NCP-1)

    sc-58072
    100 µg/ml
    $316.00