Molecular structure of Vancomycin Hydrochloride, CAS Number: 1404-93-9
Vancomycin Hydrochloride (CAS 1404-93-9)
See product citations (9)
Alternate Names:
Vancomycin Hydrochloride also known as Vancocin HCl; Vancomycine; Vancocin; Lyphocin; Vancor; Vancomycin hydrochloride; Vancocina CP; Voncon; Enterocaps; Fibrantil
Application:
Vancomycin Hydrochloride is a glycopeptide cell wall disturbing antibiotic which is effective against gram positive bacteria
CAS Number:
1404-93-9
Molecular Weight:
1485.71
Molecular Formula:
C66H75Cl2N9O24•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Vancomycin hydrochloride is a glycopeptide used in research for studying antibiotic action mechanisms and bacterial resistance. In microbiology and biochemistry laboratories, vancomycin hydrochloride is utilized as a tool to explore the integrity of bacterial cell walls, specifically targeting Gram-positive bacteria. It binds to the D-alanyl-D-alanine terminus of cell wall precursor units, inhibiting cell wall synthesis, which is a fundamental process for bacterial growth and survival. This action makes vancomycin hydrochloride a reference compound in assays to determine the susceptibility of bacteria to antibiotics. Additionally, it is used in biochemical research to investigate the pathways leading to vancomycin resistance, particularly the role of altered target sites in the bacterial cell wall.
Vancomycin Hydrochloride (CAS 1404-93-9) References
- Intravitreal injection of vancomycin in experimental staphylococcal endophthalmitis. | Homer, P., et al. 1975. Acta Ophthalmol (Copenh). 53: 311-20. PMID: 1101624
- Protective effect of inactive ingredients against nephrotoxicity of vancomycin hydrochloride in rats. | Hodoshima, N., et al. 2004. Drug Metab Pharmacokinet. 19: 68-75. PMID: 15499172
- Cradle-to-gate life cycle inventory of vancomycin hydrochloride. | Ponder, C. and Overcash, M. 2010. Sci Total Environ. 408: 1331-7. PMID: 19942254
- Comparing the efficacy of three bioceramic matrices for the release of vancomycin hydrochloride. | Jiang, PJ., et al. 2010. J Biomed Mater Res B Appl Biomater. 93: 51-8. PMID: 20024966
- Transdermal delivery of vancomycin hydrochloride using combination of nano-ethosomes and iontophoresis: in vitro and in vivo study. | Mohammed, MI., et al. 2016. Drug Deliv. 23: 1558-64. PMID: 25726990
- Chitosan coated vancomycin hydrochloride liposomes: Characterizations and evaluation. | Yang, Z., et al. 2015. Int J Pharm. 495: 508-515. PMID: 26325316
- STABILITY-INDICATING HPLC METHOD FOR DETERMINATION OF VANCOMYCIN HYDROCHLORIDE IN THE PHARMACEUTICAL DOSAGE FORMS. | Serri, A., et al. 2017. Acta Pol Pharm. 74: 73-79. PMID: 29474763
- PAMAM-dendrimer Enhanced Antibacterial Effect of Vancomycin Hydrochloride Against Gram-Negative Bacteria. | Serri, A., et al. 2018. J Pharm Pharm Sci. 22: 10-21. PMID: 30589641
- Development, Evaluation, and Pharmacokinetic Assessment of Polymeric Microarray Patches for Transdermal Delivery of Vancomycin Hydrochloride. | Ramadon, D., et al. 2020. Mol Pharm. 17: 3353-3368. PMID: 32706591
- Transdermal delivery of vancomycin hydrochloride: Influence of chemical and physical permeation enhancers. | Datta, D., et al. 2021. Int J Pharm. 602: 120663. PMID: 33933644
- A transferosome-loaded bigel for enhanced transdermal delivery and antibacterial activity of vancomycin hydrochloride. | Maji, R., et al. 2021. Int J Pharm. 607: 120990. PMID: 34389419
- Borneol-based antisolvent-induced in situ forming matrix for crevicular pocket delivery of vancomycin hydrochloride. | Lertsuphotvanit, N., et al. 2022. Int J Pharm. 617: 121603. PMID: 35192882
- In Vitro Nephrotoxicity and Permeation of Vancomycin Hydrochloride Loaded Liposomes. | Papp, N., et al. 2022. Pharmaceutics. 14: PMID: 35745726
- Effect of vancomycin hydrochloride on Staphylococcus epidermidis biofilm associated with silicone elastomer. | Evans, RC. and Holmes, CJ. 1987. Antimicrob Agents Chemother. 31: 889-94. PMID: 3619420
- Colorimetric assay and improved method for identification of vancomycin hydrochloride. | Fooks, JR., et al. 1968. J Pharm Sci. 57: 315-7. PMID: 5641679
- Structure of vancomycin and its complex with acetyl-D-alanyl-D-alanine. | Sheldrick, GM., et al. 1978. Nature. 271: 223-5. PMID: 622161
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Vancomycin Hydrochloride, 250 mg | sc-204938 | 250 mg | $90.00 | |||
Vancomycin Hydrochloride, 1 g | sc-204938A | 1 g | $176.00 |