Valproic Acid Antibody (804): sc-58069

Valproic Acid Antibody (804) is a mouse monoclonal IgG1 antibody that detects Valproic Acid with species reactivity in non-species reactive (NSR) samples by enzyme-linked immunosorbent assay (ELISA). Valproic Acid (804) antibody is available in a non-conjugated form, providing flexibility for various experimental setups. Valproic Acid, a fatty acid, serves as an essential anticonvulsant and mood-stabilizing agent, primarily utilized in the management of epilepsy and bipolar disorder, while also being effective in treating migraine headaches and schizophrenia. Valproic Acid′s importance lies in its multifaceted mechanism of action; enhancing γ-Aminobutyric acid levels, a key inhibitory neurotransmitter in the brain, while inhibiting histone deacetylase 1 (HDAC1), which plays a crucial role in gene expression regulation. This inhibition is particularly significant in neuroprotective therapies, including those targeting HIV, as Valproic Acid may help in modulating neuronal survival and function. With a molecular weight of 144.211 g/mol and a half-life of 9-16 hours, Valproic Acid is primarily metabolized in the liver to its glucuronide conjugate, making Valproic Acid a vital compound in pharmacological treatments. Common side effects include dyspepsia and weight gain, which are important considerations for patient management.