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![[Val5]-Angiotensin II acetate salt - chemical structure image](https://media.scbt.com/product/val5-angiotensin-ii-acetate-salt-58-49-1-non-salt-structure_14_23_t_142348.jpg "Molecular structure of [Val5]-Angiotensin II acetate salt")
Molecular structure of [Val5]-Angiotensin II acetate salt
[Val5]-Angiotensin II acetate salt (CAS 58-49-1 (non-salt))
CAS Number:
58-49-1 (non-salt)
Purity:
≥95%
Molecular Weight:
1032.15 (anhydrous free base)
Molecular Formula:
C49H69N13O12•xC2H4O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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[Val5]-Angiotensin II acetate salt hydrate is frequently used in biochemical research, particularly in studies related to the renin-angiotensin system and its role in regulating blood pressure and fluid balance. This modified peptide is utilized to understand the binding affinity and interaction with angiotensin receptors, which are pivotal in cardiovascular physiology. Researchers employ [Val5]-Angiotensin II acetate salt hydrate in experiments designed to elucidate the pathways and mechanisms by which angiotensin influences vascular tone and renal function. Moreover, it is used to investigate the potential effects of altered angiotensin peptides on receptor activation and signaling pathways.
[Val5]-Angiotensin II acetate salt (CAS 58-49-1 (non-salt)) References
- The ROS derived mitochondrial respirstion not from NADPH oxidase plays key role in Celastrol against angiotensin II-mediated HepG2 cell proliferation. | Liu, X., et al. 2016. Apoptosis. 21: 1315-1326. PMID: 27658784
- Telmisartan Restricts Chikungunya Virus Infection In Vitro and In Vivo through the AT1/PPAR-γ/MAPKs Pathways. | De, S., et al. 2022. Antimicrob Agents Chemother. 66: e0148921. PMID: 34748384
- Salicylic Acid Conjugate of Telmisartan Inhibits Chikungunya Virus Infection and Inflammation. | Dash, RN., et al. 2024. ACS Omega. 9: 146-156. PMID: 38222605
- Relative biological activities of Asn1-,Val5-angiotensin II, Ile5-angiotensin II and Sar1-angiotensin II in man. | Kono, T., et al. 1985. Life Sci. 37: 365-9. PMID: 3892218
- Physiological doses of [Ile5]- and [Val5]-Angiotensin II fail to increase plasma catecholamines at the peak pressor response in rats. | Butler, DG. and Butt, DA. 1995. Arch Int Pharmacodyn Ther. 329: 272-82. PMID: 8540766
- Purification and characterization of angiotensin II degradation factor from porcine endothelial cells. | Fujioka, H., et al. 1995. Tohoku J Exp Med. 177: 183-92. PMID: 8966715
- Cardiovascular responses in vivo to angiotensin II and the peptide antagonist saralasin in rainbow trout Oncorhynchus mykiss. | Fuentes, J. and Eddy, FB. 1998. J Exp Biol. 201: 267-72. PMID: 9405316
- Renal uptake of circulating angiotensin II in Val5-angiotensin II infused rats is mediated by AT1 receptor. | Zou, LX., et al. 1998. Am J Hypertens. 11: 570-8. PMID: 9633793
- The Effects of Angiotensin II, Olmesartan and PD123, 319 on Protein Kinase C in STZ Induced Rat Vascular Smooth Muscle Cell Culture | ÇİÇEK, Z., AKILLIOĞLU, K., & DOĞAN, A. 2023. Black Sea Journal of Health Science. 6(1): 127-133.
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AT1.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
[Val5]-Angiotensin II acetate salt, 5 mg | sc-301966 | 5 mg | $106.00 |