utrophin Antibody (55): sc-136116
- utrophin Antibody (55) is a mouse monoclonal IgG1 provided at 50 µg/500 µl
- raised against amino acids 768-874 of utrophin of mouse origin
- recommended for detection of utrophin of mouse origin by WB and IP
- See utrophin (8A4): sc-33700 for utrophin antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for utrophin Antibody (55). This work is in progress.
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SEE ALSO...
Utrophin Antibody (55) is a mouse monoclonal IgG1 antibody that detects utrophin in mouse samples through applications such as western blotting (WB) and immunoprecipitation (IP). Utrophin is a crucial structural protein that shares significant homology with dystrophin and plays a vital role in anchoring the cytoskeleton to the plasma membrane, particularly in muscle and brain tissues. Utrophin localization to the inner surface of the plasma membrane is essential for maintaining cellular integrity and facilitating communication between the cytoskeleton and the extracellular matrix. Notably, utrophin undergoes alternative splicing, which allows interactions with various proteins, contributing to functional versatility. Utrophin importance is underscored in muscular dystrophies, where upregulation has been shown to mitigate dystrophic pathology, suggesting a potential therapeutic avenue for conditions like Duchenne muscular dystrophy. Anti-utrophin antibody (55) enables researchers to gain insights into utrophin expression dynamics and interactions, furthering understanding of muscle biology and disease mechanisms.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
utrophin Antibody (55) | sc-136116 | 50 µg/500 µl | $322.00 |