URO-10 Antibody (T43): sc-58889
- URO-10 Antibody (T43) is a mouse monoclonal IgG1 κ URO-10 antibody, cited in 1 publications, provided at 200 µg/ml
- raised against T24 bladder cancer cell line of human origin
- URO-10 Antibody (T43) is recommended for detection of URO-10 of human origin by IF
- Anti-URO-10 Antibody (T43) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for URO-10 Antibody (T43). These reagents are now offered in bundles with URO-10 Antibody (T43) (see ordering information below).
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URO-10 Antibody (T43) is a mouse monoclonal IgG1 kappa light chain antibody that detects URO-10 protein of human origin by immunofluorescence (IF). URO-10 (T43) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates, providing versatility for different experimental needs. URO-10 protein is a surface glycoprotein predominantly found in the urothelium, which is the specialized tissue lining the urinary tract, including the renal pelvis, ureters, bladder, and parts of the urethra. URO-10 plays a crucial role in maintaining the integrity of the urothelium, which serves as a permeability barrier to protect underlying tissues from harmful substances in urine while also allowing for the necessary expansion and contraction of the bladder. The unique structure of URO-10, characterized by its glycosylation patterns, is essential for its function in cell signaling and interaction with other proteins, which can influence cellular responses to injury and inflammation. URO-10 is also expressed in invasive bladder tumors and various other cancers, making URO-10 a significant marker for cancer research and potential therapeutic targeting. URO-10 expression in basal cell layers of the skin, exocervix, esophagus, and occasional cells in the thymus further highlights URO-10′s relevance in both normal physiology and pathological conditions.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
URO-10 Antibody (T43) References:
- Immunobiologic, cytogenetic and drug response features of a newly established cell line (SCRC-1) from renal small cell carcinoma. | Chuang, CK., et al. 2000. J Urol. 163: 1016-21. PMID: 10688041
- Cellular origin of renal cell carcinoma--an immunohistological study on monoclonal antibodies. | Gu, FL., et al. 1991. Scand J Urol Nephrol Suppl. 138: 203-6. PMID: 1785005
- Histogenesis of renal cell carcinoma and renal oncocytoma. An immunohistochemical study. | Cohen, C., et al. 1988. Cancer. 62: 1946-51. PMID: 2458824
- Definition of the human renal cell carcinoma phenotype using monoclonal and polyclonal antibodies: a tumor marker study. | Blouin, P., et al. 1989. Exp Pathol. 36: 147-63. PMID: 2668015
- Analysis of a mouse monoclonal antibody that reacts with a specific region of the human proximal tubule and subsets renal cell carcinomas. | Bander, NH., et al. 1989. Cancer Res. 49: 6774-80. PMID: 2684399
- Failure of cytotoxic chemotherapy, 1983-1988, and the emerging role of monoclonal antibodies for renal cancer. | Yagoda, A. and Bander, NH. 1989. Urol Int. 44: 338-45. PMID: 2696193
- Cell surface antigens of human bladder cancer defined by mouse monoclonal antibodies. | Fradet, Y., et al. 1984. Proc Natl Acad Sci U S A. 81: 224-8. PMID: 6364135
- [Distribution pattern of urothelial associated glycoproteins in human bladder cancer cell lines in in vitro culture]. | Knuechel, R., et al. 1993. Verh Dtsch Ges Pathol. 77: 256-9. PMID: 7511293
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
URO-10 Antibody (T43) | sc-58889 | 200 µg/ml | $322.00 | |||
URO-10 Antibody (T43): m-IgG Fc BP-HRP Bundle | sc-526918 | 200 µg Ab; 10 µg BP | $361.00 | |||
URO-10 Antibody (T43): m-IgG1 BP-HRP Bundle | sc-532291 | 200 µg Ab; 20 µg BP | $361.00 | |||
URO-10 Antibody (T43) AC | sc-58889 AC | 500 µg/ml, 25% agarose | $424.00 | |||
URO-10 Antibody (T43) HRP | sc-58889 HRP | 200 µg/ml | $322.00 | |||
URO-10 Antibody (T43) FITC | sc-58889 FITC | 200 µg/ml | $336.00 | |||
URO-10 Antibody (T43) PE | sc-58889 PE | 200 µg/ml | $349.00 | |||
URO-10 Antibody (T43) Alexa Fluor® 488 | sc-58889 AF488 | 200 µg/ml | $364.00 | |||
URO-10 Antibody (T43) Alexa Fluor® 546 | sc-58889 AF546 | 200 µg/ml | $364.00 | |||
URO-10 Antibody (T43) Alexa Fluor® 594 | sc-58889 AF594 | 200 µg/ml | $364.00 | |||
URO-10 Antibody (T43) Alexa Fluor® 647 | sc-58889 AF647 | 200 µg/ml | $364.00 | |||
URO-10 Antibody (T43) Alexa Fluor® 680 | sc-58889 AF680 | 200 µg/ml | $364.00 | |||
URO-10 Antibody (T43) Alexa Fluor® 790 | sc-58889 AF790 | 200 µg/ml | $364.00 |