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Uridine 5′-triphosphate tris salt (CAS 108321-53-5)

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Alternate Names:
Uridine 5′-triphosphoric acid; UTP
Application:
Uridine 5′-triphosphate tris salt is a P2Y receptor agonist
CAS Number:
108321-53-5
Purity:
≥90%
Molecular Weight:
605.28
Molecular Formula:
C9H15N2O15P3•C4H11NO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Uridine 5′-triphosphate tris salt is primarily used in biochemical and molecular biology research, where it serves as a substrate for enzymes like RNA polymerases during the synthesis of RNA in vitro transcription experiments. It is also used in studies involving nucleotide receptors, where its role as an agonist for P2Y receptors is analyzed to understand signal transduction pathways. In addition, uridine 5′-triphosphate tris salt is instrumental in the investigation of nucleotide metabolism and the enzymatic processes that regulate the synthesis and breakdown of RNA. It is a key reagent in enzymology assays that explore the function and kinetics of kinases and phosphorylases. Moreover, this compound plays a significant role in the study of energy transfer and storage mechanisms within cells, as triphosphate nucleotides are essential for the synthesis of ATP.


Uridine 5′-triphosphate tris salt (CAS 108321-53-5) References

  1. Two-step method to isolate target recombinant protein from co-purified bacterial contaminant SlyD after immobilised metal affinity chromatography.  |  Parsy, CB., et al. 2007. J Chromatogr B Analyt Technol Biomed Life Sci. 853: 314-9. PMID: 17459787
  2. Influence of hydrodynamic conditions on quantitative cellular assays in microfluidic systems.  |  Yin, H., et al. 2007. Anal Chem. 79: 7139-44. PMID: 17658886
  3. Activation of P2Y receptors by ATP and by its analogue, ADPbetaS, triggers two calcium signal pathways in the longitudinal muscle of mouse distal colon.  |  Zizzo, MG., et al. 2008. Eur J Pharmacol. 595: 84-9. PMID: 18713670
  4. Purinergic neuron-to-glia signaling in the enteric nervous system.  |  Gulbransen, BD. and Sharkey, KA. 2009. Gastroenterology. 136: 1349-58. PMID: 19250649
  5. P2X7-dependent, but differentially regulated release of IL-6, CCL2, and TNF-α in cultured mouse microglia.  |  Shieh, CH., et al. 2014. Glia. 62: 592-607. PMID: 24470356
  6. A photo-regulated aptamer sensor for spatiotemporally controlled monitoring of ATP in the mitochondria of living cells.  |  Hong, S., et al. 2019. Chem Sci. 11: 713-720. PMID: 34123044

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Uridine 5′-triphosphate tris salt, 100 mg

sc-213136
100 mg
$189.00

Uridine 5′-triphosphate tris salt, 500 mg

sc-213136A
500 mg
$715.00