Date published: 2025-12-18

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Uridine 5′-monophosphate (CAS 58-97-9)

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Alternate Names:
U 5′-P; UMP; Uridylic acid
CAS Number:
58-97-9
Purity:
≥98%
Molecular Weight:
324.18
Molecular Formula:
C9H13N2O9P
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Uridine 5′-monophosphate is a nucleotide that plays an integral role in the synthesis of RNA and the regulation of various biochemical pathways. In research applications, it is often used to investigate RNA structure and function, as well as the mechanisms of RNA synthesis. Studies involving Uridine 5′-monophosphate also focus on its role in nucleotide metabolism, where it participates as a substrate for the synthesis of nucleic acids. Additionally, it is of interest in enzymology, as researchers examine the kinetics and specificity of enzymes like kinases and phosphatases that act upon this compound. Furthermore, Uridine 5′-monophosphate is utilized in studies on cellular signaling and energy transfer, as it contributes to the pool of nucleotides necessary for these critical cellular processes.


Uridine 5′-monophosphate (CAS 58-97-9) References

  1. Copper(II) complexes with uridine, uridine 5'-monophosphate, spermidine, or spermine in aqueous solution.  |  Lomozik, L. and Jastrzab, R. 2003. J Inorg Biochem. 93: 132-40. PMID: 12576275
  2. Non-covalent and coordination interactions in Cu(II) systems with uridine, uridine 5'-monophosphate and triamine or tetramine as biogenic amine analogues in aqueous solutions.  |  Łomozik, L. and Jastrzab, R. 2003. J Inorg Biochem. 97: 179-90. PMID: 14512196
  3. The cardioprotective effect of uridine and uridine-5'-monophosphate: the role of the mitochondrial ATP-dependent potassium channel.  |  Krylova, IB., et al. 2006. Exp Gerontol. 41: 697-703. PMID: 16621391
  4. Dietary supplementation with uridine-5'-monophosphate (UMP), a membrane phosphatide precursor, increases acetylcholine level and release in striatum of aged rat.  |  Wang, L., et al. 2007. Brain Res. 1133: 42-8. PMID: 17184749
  5. Comparative study of cardioprotective effects of uridine-5'-monophosphate and uridine-5'-triphosphate during the early periods of acute myocardial ischemia.  |  Bul'on, VV., et al. 2007. Bull Exp Biol Med. 144: 322-5. PMID: 18457027
  6. Inhibition of orotidine-5'-monophosphate decarboxylase--discoveries and lessons.  |  Kotra, LP. and Pai, EF. 2008. Nucleic Acids Symp Ser (Oxf). 85-6. PMID: 18776265
  7. Effects of dietary uridine 5'-monophosphate on immune responses in newborn calves.  |  Mashiko, T., et al. 2009. J Anim Sci. 87: 1042-7. PMID: 19228994
  8. Structure of bovine pancreatic ribonuclease complexed with uridine 5'-monophosphate at 1.60 A resolution.  |  Larson, SB., et al. 2010. Acta Crystallogr Sect F Struct Biol Cryst Commun. 66: 113-20. PMID: 20124705
  9. Proton transfer from C-6 of uridine 5'-monophosphate catalyzed by orotidine 5'-monophosphate decarboxylase: formation and stability of a vinyl carbanion intermediate and the effect of a 5-fluoro substituent.  |  Tsang, WY., et al. 2012. J Am Chem Soc. 134: 14580-94. PMID: 22812629
  10. Phosphorylation of uridine and cytidine by uridine-cytidine kinase.  |  Qian, Y., et al. 2014. J Biotechnol. 188: 81-7. PMID: 25160914
  11. Antiarrhythmic effect of uridine and uridine-5'-monophosphate in acute myocardial ischemia.  |  Bul'on, VV., et al. 2014. Bull Exp Biol Med. 157: 728-31. PMID: 25339588
  12. A novel procedure for purification of uridine 5'-monophosphate based on adsorption methodology using a hyper-cross-linked resin.  |  Wu, J., et al. 2015. Bioprocess Biosyst Eng. 38: 967-79. PMID: 25575762
  13. The biosynthesis of uridine 5'-monophosphate in Giardia lamblia.  |  Vitti, GF., et al. 1987. Int J Parasitol. 17: 805-12. PMID: 3570646
  14. Underlying antihypertensive mechanism of egg white-derived peptide QIGLF using renal metabolomics analysis.  |  Yu, Z., et al. 2022. Food Res Int. 157: 111457. PMID: 35761693
  15. Coordination Chemistry of Phosphate Groups in Systems Including Copper(II) Ions, Phosphoethanolamine and Pyrimidine Nucleotides.  |  Gabryel-Skrodzka, M., et al. 2022. Int J Mol Sci. 23: PMID: 36430195

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Uridine 5′-monophosphate, 1 g

sc-216044
1 g
$250.00