Date published: 2025-12-5

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Uridine 5′-diphosphoglucuronic acid trisodium salt (CAS 63700-19-6)

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Alternate Names:
Uridine 5′-diphosphoglucuronic acid trisodium salt is also known as Trisodium UDP-glucuronic Acid.
Application:
Uridine 5′-diphosphoglucuronic acid trisodium salt is a nucleoside compound for metabolomics and proteomics research.
CAS Number:
63700-19-6
Purity:
≥98%
Molecular Weight:
646.23
Molecular Formula:
C15H19N2Na3O18P2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Uridine 5′-diphosphoglucuronic acid trisodium salt (UDPGA-Na3) is a nucleoside compound for metabolomics and proteomics research. Its also known as Trisodium UDP-glucuronic Acid and works as a reactant used in the enzymatic preparation of β-glucuronides. Uridine 5′-diphosphoglucuronic acid trisodium salt, a carboxylic acid-formed sugar nucleotide, optimizes incubation and glucuronidation assay tests. In numerous cell component biosyntheses, Uridine 5′-diphosphoglucuronic acid trisodium salt is a participant. These cell components, like glycosaminoglycans, require glycosyltransferases in their biosynthesis, for which Uridine 5′-diphosphoglucuronic acid trisodium salt is a glycosyl donor.


Uridine 5′-diphosphoglucuronic acid trisodium salt (CAS 63700-19-6) References

  1. Chemoenzymatic preparation of silybin beta-glucuronides and their biological evaluation.  |  Kren, V., et al. 2000. Drug Metab Dispos. 28: 1513-7. PMID: 11095591
  2. Biotransformation of a GABAA receptor partial agonist in sprague-dawley rats and cynomolgus monkeys: identification of two unique N-carbamoyl metabolites.  |  Shaffer, CL., et al. 2005. Drug Metab Dispos. 33: 1688-99. PMID: 16081672
  3. Automated software-guided identification of new buspirone metabolites using capillary LC coupled to ion trap and TOF mass spectrometry.  |  Fandiño, AS., et al. 2006. J Mass Spectrom. 41: 248-55. PMID: 16421870
  4. Metabolism and pharmacokinetics of rhynchophylline in rats.  |  Wang, W., et al. 2010. Biol Pharm Bull. 33: 669-76. PMID: 20410604
  5. Regioselectivity of human UDP-glucuronosyltransferase isozymes in flavonoid biotransformation by metal complexation and tandem mass spectrometry.  |  Robotham, SA. and Brodbelt, JS. 2011. Biochem Pharmacol. 82: 1764-70. PMID: 21889496
  6. Metabolism studies of ifenprodil, a potent GluN2B receptor antagonist.  |  Falck, E., et al. 2014. J Pharm Biomed Anal. 88: 96-105. PMID: 24042122
  7. Renal glucuronidation and multidrug resistance protein 2-/ multidrug resistance protein 4-mediated efflux of mycophenolic acid: interaction with cyclosporine and tacrolimus.  |  El-Sheikh, AA., et al. 2014. Transl Res. 164: 46-56. PMID: 24486136
  8. Urinary metabolite profiling identifies novel colonic metabolites and conjugates of phenolics in healthy volunteers.  |  Pimpão, RC., et al. 2014. Mol Nutr Food Res. 58: 1414-25. PMID: 24740799
  9. Identification of Human UDP-Glucuronosyltransferase 1A4 as the Major Isozyme Responsible for the Glucuronidation of 20(S)-Protopanaxadiol in Human Liver Microsomes.  |  Li, J., et al. 2016. Int J Mol Sci. 17: 205. PMID: 27005621
  10. Alamethicin for using in bioavailability studies? - Re-evaluation of its effect.  |  Vollmer, M., et al. 2017. Toxicol In Vitro. 39: 111-118. PMID: 27940284
  11. In vitro percutaneous absorption and metabolism of Bisphenol A (BPA) through fresh human skin.  |  Toner, F., et al. 2018. Toxicol In Vitro. 47: 147-155. PMID: 29154941
  12. Inhibition of cytochrome P450 enzymes and uridine 5'-diphospho-glucuronosyltransferases by vicagrel in human liver microsomes: A prediction of potential drug-drug interactions.  |  Liu, S., et al. 2022. Chem Biol Interact. 352: 109775. PMID: 34910929
  13. Species and tissue differences in regorafenib glucuronidation.  |  Kojima, A., et al. 2022. Xenobiotica. 52: 129-133. PMID: 35311470
  14. Enzymatic preparation of lysergol β-d-glucuronide  |  David E. Stevensona, et al. 2000. Collect. Czech. Chem. Commun. 65: 117-121.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Uridine 5′-diphosphoglucuronic acid trisodium salt, 5 mg

sc-216043C
5 mg
$56.00

Uridine 5′-diphosphoglucuronic acid trisodium salt, 25 mg

sc-216043
25 mg
$106.00

Uridine 5′-diphosphoglucuronic acid trisodium salt, 100 mg

sc-216043D
100 mg
$388.00

Uridine 5′-diphosphoglucuronic acid trisodium salt, 250 mg

sc-216043A
250 mg
$899.00

Uridine 5′-diphosphoglucuronic acid trisodium salt, 1 g

sc-216043B
1 g
$2958.00