Date published: 2025-11-4

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Urethane (CAS 51-79-6)

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Application:
Urethane is a naturally occurring contaminant
CAS Number:
51-79-6
Purity:
≥97%
Molecular Weight:
89.09
Molecular Formula:
C3H7NO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Urethane, also known as ethyl carbamate, is a versatile compound utilized in a wide array of research disciplines. In organic synthesis, urethane is often employed as a protecting group for amines, allowing chemists to selectively manipulate other functional groups within a molecule without interference. This utility is particularly valuable in the stepwise construction of complex organic molecules. Additionally, in polymer science, urethane is a fundamental building block in the production of polyurethanes, and research into these polymers explores their potential for creating materials with desirable properties such as elasticity, resilience, and toughness. Studies in surface chemistry also leverage urethane to modify the properties of surfaces, which can affect adhesion, permeability, and resistance characteristics.


Urethane (CAS 51-79-6) References

  1. Urethane as a carcinogen and as an anaesthetic for fishes.  |  BALL, JN. and COWEN, PN. 1959. Nature. 184(Suppl 6): 370. PMID: 13796228
  2. Mutagenicity, metabolism, and DNA interactions of urethane.  |  Sotomayor, RE. and Collins, TF. 1990. Toxicol Ind Health. 6: 71-108. PMID: 2190358
  3. Urethane-hydrolyzing enzyme from Citrobacter sp.  |  Kobashi, K., et al. 1990. Chem Pharm Bull (Tokyo). 38: 1326-8. PMID: 2393957
  4. Urethane anesthesia depresses activities of thalamocortical neurons and alters its response to nociception in terms of dual firing modes.  |  Huh, Y. and Cho, J. 2013. Front Behav Neurosci. 7: 141. PMID: 24133420
  5. Urethane anesthesia in acute lower urinary tract studies in the male rat.  |  van Asselt, E., et al. 2017. Lab Anim. 51: 256-263. PMID: 27365334
  6. Suitability of urethane anesthesia for physiopharmacological investigations in various systems. Part 1: General considerations.  |  Maggi, CA. and Meli, A. 1986. Experientia. 42: 109-14. PMID: 2868911
  7. Preparation of new low viscosity urethane dimethacrylates for dental composites.  |  Xu, Y., et al. 2018. J Biomater Sci Polym Ed. 29: 1011-1025. PMID: 28784029
  8. Inhibition of the metabolism of urethane by ethanol.  |  Yamamoto, T., et al. 1988. Drug Metab Dispos. 16: 355-8. PMID: 2900725
  9. Hazards of urethane (ethyl carbamate): a review of the literature.  |  Field, KJ. and Lang, CM. 1988. Lab Anim. 22: 255-62. PMID: 3050270
  10. Urethane anesthesia suppresses hippocampal subthreshold activity and neuronal synchronization.  |  Yagishita, H., et al. 2020. Brain Res. 1749: 147137. PMID: 33007303
  11. Urethane and contraction of vascular smooth muscle.  |  Altura, BM. and Weinberg, J. 1979. Br J Pharmacol. 67: 255-63. PMID: 497529
  12. Urethane inhibits cardiovascular responses mediated by the stimulation of alpha-2 adrenoceptors in the rat.  |  Armstrong, JM., et al. 1982. J Pharmacol Exp Ther. 223: 524-35. PMID: 6127404
  13. The kinetics of urethane elimination in the mouse.  |  O'Flaherty, EJ. and Sichak, SP. 1983. Toxicol Appl Pharmacol. 68: 354-8. PMID: 6857669

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Urethane, 25 g

sc-213134B
25 g
$32.00

Urethane, 100 g

sc-213134
100 g
$85.00

Urethane, 500 g

sc-213134A
500 g
$250.00