Uracil-5-boronic acid (CAS 70523-22-7)
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Uracil-5-boronic acid (U5BA) holds a versatile role, encompassing its utilization as an inhibitor of enzymes and receptors, a substrate for enzymatic reactions, and a fundamental building block for the synthesis of innovative compounds. As an inhibitor, Uracil-5-boronic acid exerts its influence by binding to the active site of enzymes and receptors. This binding event effectively impedes their ability to interact with their substrates, thereby leading to the inhibition of their activity. Moreover, Uracil-5-boronic acid exhibits an affinity for binding to DNA and RNA, thereby obstructing their transcription and translation processes. Through these multifaceted interactions, Uracil-5-boronic acid exerts its modulatory effects on biochemical pathways, presenting itself as useful in various scientific endeavors.
Uracil-5-boronic acid (CAS 70523-22-7) References
- Probing the interactions between boronic acids and cis-diol-containing biomolecules by affinity capillary electrophoresis. | Lü, C., et al. 2013. Anal Chem. 85: 2361-9. PMID: 23357784
- Novel 99mTc(III)-azide complexes [99mTc(N3)(CDO)(CDOH)2B-R] (CDOH2=cyclohexanedione dioxime) as potential radiotracers for heart imaging. | Liu, M., et al. 2016. Nucl Med Biol. 43: 732-741. PMID: 27632344
- Mechanism of Cu-Catalyzed Aryl Boronic Acid Halodeboronation Using Electrophilic Halogen: Development of a Base-Catalyzed Iododeboronation for Radiolabeling Applications. | Molloy, JJ., et al. 2019. Org Lett. 21: 2488-2492. PMID: 30908055
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Uracil-5-boronic acid, 250 mg | sc-264484 | 250 mg | $304.00 | |||
Uracil-5-boronic acid, 1 g | sc-264484A | 1 g | $566.00 |