Molecular structure of Umbelliferone, CAS Number: 93-35-6
Umbelliferone (CAS 93-35-6)
Alternate Names:
7-Hydroxy-2H-1-benzopyran-2-one; 7-Hydroxycoumarin
Application:
Umbelliferone is an intracellular pH sensitive fluorescent indicator & bloodbrain barrier probe
CAS Number:
93-35-6
Purity:
≥99%
Molecular Weight:
162.14
Molecular Formula:
C9H6O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Umbelliferone functions as a fluorescent dye. It is used to label and visualize cellular structures and molecules due to its ability to emit fluorescence when exposed to ultraviolet light. Umbelliferone′s mechanism of action involves binding to specific cellular components or molecules. Umbelliferone′s fluorescent properties make it useful for visualizing biological processes and interactions at the molecular and cellular level. Umbelliferone can be employed to study enzyme activity and inhibition, providing insights into biochemical pathways and cellular functions. Its mechanism of action involves interacting with enzymes and affecting their activity, making it useful for investigating various biological processes.
Umbelliferone (CAS 93-35-6) References
- Uptake and modification of umbelliferone by various seedlings. | Hijazin, T., et al. 2019. Phytochemistry. 157: 194-199. PMID: 30439620
- Umbelliferone Prevents Lipopolysaccharide-Induced Bone Loss and Suppresses RANKL-Induced Osteoclastogenesis by Attenuating Akt-c-Fos-NFATc1 Signaling. | Kwak, SC., et al. 2019. Int J Biol Sci. 15: 2427-2437. PMID: 31595160
- Xanthotoxin and umbelliferone attenuate cognitive dysfunction in a streptozotocin-induced rat model of sporadic Alzheimer's disease: The role of JAK2/STAT3 and Nrf2/HO-1 signalling pathway modulation. | Hindam, MO., et al. 2020. Phytother Res. 34: 2351-2365. PMID: 32250498
- Glutaminase inhibitory activity of umbelliferone isolated from kabosu (Citrus sphaerocarpa Hort. ex Tanaka). | Shimada, A., et al. 2022. Nat Prod Res. 36: 605-609. PMID: 32619101
- Umbelliferone (7-hydroxycoumarin): A non-toxic antidiarrheal and antiulcerogenic coumarin. | Cruz, LF., et al. 2020. Biomed Pharmacother. 129: 110432. PMID: 32768935
- Umbelliferone attenuates gentamicin-induced renal toxicity by suppression of TLR-4/NF-κB-p65/NLRP-3 and JAK1/STAT-3 signaling pathways. | Hassanein, EHM., et al. 2021. Environ Sci Pollut Res Int. 28: 11558-11571. PMID: 33128149
- Ameliorative effect of umbelliferone in remote organ injury induced by renal ischemia-reperfusion in rats. | Icoglu Aksakal, F., et al. 2021. J Food Biochem. 45: e13628. PMID: 33502024
- Umbelliferone alleviates hepatic ischemia/reperfusion-induced oxidative stress injury via targeting Keap-1/Nrf-2/ARE and TLR4/NF-κB-p65 signaling pathway. | Hassanein, EHM., et al. 2021. Environ Sci Pollut Res Int. 28: 67863-67879. PMID: 34268687
- Umbelliferone attenuates glycerol-induced myoglobinuric acute kidney injury through peroxisome proliferator-activated receptor-γ agonism in rats. | Kaur, T., et al. 2021. J Biochem Mol Toxicol. 35: e22892. PMID: 34409680
- Umbelliferone prevents isoproterenol-induced myocardial injury by upregulating Nrf2/HO-1 signaling, and attenuating oxidative stress, inflammation, and cell death in rats. | Althunibat, OY., et al. 2022. Biomed Pharmacother. 149: 112900. PMID: 35378502
- [Umbelliferone improves chronic hypoxia-induced pulmonary hypertension by inhibiting the RhoA/ROCK signaling pathway and autophagy]. | Shang, P., et al. 2022. Sheng Li Xue Bao. 74: 555-562. PMID: 35993207
- Umbelliferone Inhibits Migration, Invasion and Inflammation of Rheumatoid Arthritis Fibroblast-Like Synoviocytes and Relieves Adjuvant-Induced Arthritis in Rats by Blockade of Wnt/β-Catenin Signaling Pathway. | Cai, L., et al. 2022. Am J Chin Med. 50: 1945-1962. PMID: 35997647
- Umbelliferone protects against methylglyoxal-induced HUVECs dysfunction through suppression of apoptosis and oxidative stress. | Zhang, S., et al. 2023. J Appl Toxicol. 43: 490-499. PMID: 36170298
- The Antivirulence Activity of Umbelliferone and Its Protective Effect against A. hydrophila-Infected Grass Carp. | Zhao, L., et al. 2022. Int J Mol Sci. 23: PMID: 36232424
- Umbelliferone protects against cerebral ischemic injury through selective autophagy of mitochondria. | Zhou, Z., et al. 2023. Neurochem Int. 165: 105520. PMID: 36933866
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T2R38.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Umbelliferone, 25 g | sc-208477 | 25 g | $86.00 | |||
Umbelliferone, 100 g | sc-208477A | 100 g | $273.00 | |||
Umbelliferone, 250 g | sc-208477B | 250 g | $398.00 | |||
Umbelliferone, 1 kg | sc-208477C | 1 kg | $1581.00 |