ULK4 Antibody (MH-49): sc-135595
- ULK4 Antibody (MH-49) is a mouse monoclonal IgG1 κ ULK4 antibody provided at 100 µg/ml
- raised against recombinant ULK4 proULK4tULK4ein of human origin
- recommended for detection of ULK4 of human origin by WB, IP and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for ULK4 Antibody (MH-49). This work is in progress.
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ULK4 Antibody (MH-49) is a mouse monoclonal IgG1 kappa light chain antibody that detects ULK4 protein of human origin by western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). Anti-ULK4 antibody (MH-49) is available as a non-conjugated format. ULK4 protein, which consists of 1,275 amino acids, plays a crucial role in cellular processes by being part of the serine/threonine protein kinase family, which is essential for the phosphorylation and dephosphorylation of proteins on serine and threonine residues. This post-translational modification is vital for regulating a wide array of cellular functions, including cell division, homeostasis, and apoptosis. ULK4 contains one protein kinase domain and one HEAT repeat, and while ULK4 is believed to have a catalytically inactive domain, ULK4 may still influence the ATP-dependent phosphorylation of target proteins. The gene encoding ULK4 is located on human chromosome 3, a region that is significant due to its housing of over 1,100 genes, including those related to chemokine receptors and various cancer-related loci. Understanding the function and regulation of ULK4 is important for elucidating potential roles in cancer biology and other diseases, making ULK4 (MH-49) antibody a valuable tool for researchers studying these pathways.
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ULK4 Antibody (MH-49) References:
- The protein kinase complement of the human genome. | Manning, G., et al. 2002. Science. 298: 1912-34. PMID: 12471243
- Protein kinase catalytic domain sequence database: identification of conserved features of primary structure and classification of family members. | Hanks, SK. and Quinn, AM. 1991. Methods Enzymol. 200: 38-62. PMID: 1956325
- The protein kinase family: conserved features and deduced phylogeny of the catalytic domains. | Hanks, SK., et al. 1988. Science. 241: 42-52. PMID: 3291115
- Sequence patterns in protein kinases. | Bairoch, A. and Claverie, JM. 1988. Nature. 331: 22. PMID: 3340146
- Protein kinases share a common structural motif outside the conserved catalytic domain. | Véron, M., et al. 1994. Cell Mol Biol (Noisy-le-grand). 40: 587-96. PMID: 7981616
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ULK4 Antibody (MH-49) | sc-135595 | 100 µg/ml | $339.00 |