Date published: 2025-10-20

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Ubiquitin Isopeptidase Inhibitor II, F6 (CAS 157654-67-6 (HCl salt))

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Application:
Ubiquitin Isopeptidase Inhibitor II, F6 is a cell-permeable caspase activation and apoptosis inducer
CAS Number:
157654-67-6 (HCl salt)
Molecular Weight:
303.4
Molecular Formula:
C21H21NO
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Cell-permeable cross-conjugated alpha,beta-unsaturated dienone compound that induces caspase activation and apoptosis (IC50 = 15.65 and 16.23 µM in E1A and E1A/C9DN cells, respectively) via the apoptosome-independent mitochondrial pathway, selectively inhibiting ubiquitin isopeptidase activity. The cellular expression of Bax and Bak is essential for F6-activated apoptosis, while Bcl-2 appears to protect cells against the effect of F6.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Ubiquitin Isopeptidase Inhibitor II, F6, 10 mg

sc-296678
10 mg
$88.00