Molecular structure of Ubiquinone-10, CAS Number: 606-06-4
Ubiquinone-10 (CAS 606-06-4)
Alternate Names:
Coenzyme Q2; 2,3-Dimethoxy-5-methyl-6-geranyl-1,4-benzoquinone
Application:
Ubiquinone-10 is an inhibitor of the mitochondrial permeability transition pore
CAS Number:
606-06-4
Purity:
≥90%
Molecular Weight:
318.4
Molecular Formula:
C19H26O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Ubiquinone-10 acts as an inhibitor of the mitochondrial permeability transition pore (MPTP). This inhibitory effect can be counteracted by ubiquinone-5
Ubiquinone-10 (CAS 606-06-4) References
- Simultaneous detection of ubiquinol-10, ubiquinone-10, and tocopherols in human plasma microsamples and macrosamples as a marker of oxidative damage in neonates and infants. | Menke, T., et al. 2000. Anal Biochem. 282: 209-17. PMID: 10873275
- Inositol trisphosphate receptor calcium release is required for cerebral artery smooth muscle cell proliferation. | Wilkerson, MK., et al. 2006. Am J Physiol Heart Circ Physiol. 290: H240-7. PMID: 16113072
- Determination of the ubiquinol-10 and ubiquinone-10 (coenzyme Q10) in human serum by liquid chromatography tandem mass spectrometry to evaluate the oxidative stress. | Ruiz-Jiménez, J., et al. 2007. J Chromatogr A. 1175: 242-8. PMID: 17996879
- Stopped-flow kinetic study of the regeneration reaction of tocopheroxyl radical by reduced ubiquinone-10 in solution. | Mukai, K., et al. 1990. Biochim Biophys Acta. 1035: 77-82. PMID: 2383582
- Ubiquinone-10 alters mechanical properties and increases stability of phospholipid membranes. | Agmo Hernández, V., et al. 2015. Biochim Biophys Acta. 1848: 2233-43. PMID: 25986530
- A Self-Assembled Respiratory Chain that Catalyzes NADH Oxidation by Ubiquinone-10 Cycling between Complex I and the Alternative Oxidase. | Jones, AJ., et al. 2016. Angew Chem Int Ed Engl. 55: 728-31. PMID: 26592861
- An Improvement of Oxidative Stress in Diabetic Rats by Ubiquinone-10 and Ubiquinol-10 and Bioavailability after Short- and Long-Term Coenzyme Q10 Supplementation. | Prangthip, P., et al. 2016. J Diet Suppl. 13: 647-59. PMID: 27064932
- Effect of ubiquinone-10 on the stability of biomimetic membranes of relevance for the inner mitochondrial membrane. | Eriksson, EK., et al. 2018. Biochim Biophys Acta Biomembr. 1860: 1205-1215. PMID: 29470946
- UBIQUINONE-10 AS AN ANTIOXIDANT | DAVID PETILLO, HERBERT O. HULTIN. 2008. Journal of food biochemistry,.
- Microencapsulation of ubiquinone-10 in carbohydrate matrices for improved stability | Mahesh V. Bule a, Rekha S. Singhal a, John F. Kennedy b. 2010. Carbohydrate Polymers. 82: 1290-1296.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ubiquinone-10, 2 mg | sc-202375 | 2 mg | $40.00 | |||
Ubiquinone-10, 10 mg | sc-202375A | 10 mg | $192.00 |