Molecular structure of U 93631, CAS Number: 152273-12-6
U 93631 (CAS 152273-12-6)
Application:
U 93631 is a GABAA receptor antagonist
CAS Number:
152273-12-6
Molecular Weight:
299.37
Molecular Formula:
C17H21N3O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Available in US only.
Available in US only.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
U 93631 is a GABAA receptor antagonist that binds picrotoxin site and stabilizes the inactive form of the channel via allosteric interaction. U 93631 accelerates decay of GABA-induced Cl- currents with little effect on peak amplitude. This compound also inhibits 5-HT3A receptors via a similar mechanism.
U 93631 (CAS 152273-12-6) References
Dillon et al (1993) U-93631 causes rapid decay of g-aminobutyric acid-induced chloride currents in recombinant rat g-aminobutyric acid type A receptors. Mol.Pharmacol. 44 860. Dillon et al (1995) [4-Dimethyl-3-t-butylcarboxyl-4,5-dihydro (1,5-a) quinoxaline] is a novel ligand to the picrotoxin site on GABAA receptors, and decreases single-channel open probability. J.Pharmacol.Exp.Ther. 272 597. Das et al (2003) The GABAA receptor antagonist picrotoxin inhibits 5-hydroxytryptamine type 3A receptors. Neuropharmacology 44 431.Inhibitor of:
GABA Receptor.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
U 93631, 10 mg | sc-204364 | 10 mg | $169.00 | |||
| US: Only available in the US | ||||||
U 93631, 50 mg | sc-204364A | 50 mg | $715.00 | |||
| US: Only available in the US | ||||||