Molecular structure of U 90042, CAS Number: 134516-99-7
U 90042 (CAS 134516-99-7)
Application:
U 90042 is a GABAA receptor ligand
CAS Number:
134516-99-7
Molecular Weight:
352.78
Molecular Formula:
C17H13ClN6O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
GABAA receptor ligand that binds with comparable affinities to three receptor subtypes: α1β2γ2, α3β2γ2 and α6β2γ2 (Ki values are 7.8, 9.5 and 11.0 nM respectively). Potentiates GABA-induced chloride currents in α6β2γ2 receptors. Sedative/hypnotic compound.
U 90042 (CAS 134516-99-7) References
- Electroencephalographic properties of zaleplon, a non-benzodiazepine sedative/hypnotic, in rats. | Noguchi, H., et al. 2004. J Pharmacol Sci. 94: 246-51. PMID: 15037809
- Coronaridine congeners potentiate GABAA receptors and induce sedative activity in mice in a benzodiazepine-insensitive manner. | Arias, HR., et al. 2020. Prog Neuropsychopharmacol Biol Psychiatry. 101: 109930. PMID: 32194202
Substrate of:
GABA Receptor.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
U 90042, 10 mg | sc-204362 | 10 mg | $155.00 | |||
U 90042, 50 mg | sc-204362A | 50 mg | $620.00 |